Evidence map›Paper›PMID 39439789›Full record

ArticleFrontiers in immunology2024

Case report: Intralesional secukinumab injection for pediatric nail psoriasis: does it have to be a positive outcome?

Xuesong Wang, Yonghu Sun, Weixing Xie, Hong Liu, Guoyan Liu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuesong WangDermatology Department, Shandong Provincial Hospital for Skin Diseases, Shandong First Medical University, Jinan, China.
Yonghu SunDermatology Department, Shandong Provincial Hospital for Skin Diseases, Shandong First Medical University, Jinan, China.
Weixing XieDermatology Department, Shandong Provincial Hospital for Skin Diseases, Shandong First Medical University, Jinan, China.
Hong LiuDermatology Department, Shandong Provincial Hospital for Skin Diseases, Shandong First Medical University, Jinan, China.
Guoyan LiuDermatology Department, Shandong Provincial Hospital for Skin Diseases, Shandong First Medical University, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent studies have shown that local injection of secukinumab can achieve positive therapeutic effects when applied in the treatment of nail psoriasis. At present, there have been no other studies on the use of biological agents in the treatment of pediatric nail psoriasis. Three children were included in the study to evaluate the efficacy and safety of periungual injection and long-term injection of secukinumab in the treatment of nail psoriasis in children. It was found that local injection did not achieve a remarkable therapeutic effect. The nail lesions were improved continuously by subcutaneous injection once a month.

Indexed as

Antibodies, Monoclonal, HumanizedInjections, IntralesionalNail DiseasesPsoriasisAdolescentChildFemaleHumansInjections, SubcutaneousMaleNailsTreatment OutcomeAntibodies, Monoclonal, Humanizedsecukinumabintralesional injectionnail psoriasispediatricpsoriasissecukinumab

Identifiers

PMID39439789
PMCPMC11495258

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.