Evidence map›Paper›PMID 39439706›Full record

ArticleArchives of medical science : AMS2024

Polymorphism rs662 (Q192R) of paraoxonase-1 and susceptibility to atherosclerosis of the coronary arteries.

Malgorzata Baranska, Mariola Rychlik-Sych, Michal Dudarewicz, Anna Wiktorowska-Owczarek, Jacek Owczarek

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of medical science : AMS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Association ofInternational journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Malgorzata BaranskaDepartment of Hospital Pharmacy, Laboratory of Pharmacogenetics, Medical University of Lodz, Poland.
Mariola Rychlik-SychDepartment of Hospital Pharmacy, Laboratory of Pharmacogenetics, Medical University of Lodz, Poland.
Michal DudarewiczDepartment of Hospital Pharmacy, Laboratory of Pharmacogenetics, Medical University of Lodz, Poland.
Anna Wiktorowska-OwczarekDepartment of Pharmacology and Toxicology, Medical University of Lodz, Poland.
Jacek OwczarekDepartment of Hospital Pharmacy, Laboratory of Pharmacogenetics, Medical University of Lodz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The present study concerns a connection of the Q192RPON1 polymorphism with atherosclerosis requiring percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) in the Polish population. Methods: A total of 282 individuals who underwent coronary angiography took part in this study. The polymorphism was determined with the PCR-RFLP method. Results: The odds ratio for atherosclerosis in carriers of the 192RR genotype was 2.50 ( Conclusions: The presence of the 192RR genotype and 192R allele are indicative of at least a two-fold increased risk of atherosclerosis requiring PCI or CABG in the Polish population.

Indexed as

atherosclerosisgenetic polymorphismparaoxonase 1 (PON1)

Identifiers

PMID39439706
PMCPMC11493066

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.