A Rare Case of Neuropathic Pain in Cutis Verticis Gyrata: A Review of Contemporary Literature.

Cutis verticis gyrata (CVG) is a rare benign neurocutaneous condition marked by thickened scalp folds resembling cerebral gyri and sulci. It has been classified into primary essential, primary non-essential, and secondary types. The primary essential type is idiopathic, and the primary non-essential type may be associated with neurological or ophthalmological complications. Secondary CVG occurs more commonly than primary CVG, affects both genders at any age, and can be associated with endocrinal disorders, tumors, inflammatory diseases, or genetic conditions. For every 38.46 male cases, only one female case is known. This report aims to inform about a rare case of primary CVG in a 35-year-old female patient presenting with neuropathic pain localized to the affected area, a complication not previously documented in the literature. Heightened sensitivity to light touch and pinprick sensation in the high parietal scalp region was indicative of neuropathic pain. This report also highlights the importance of a multidisciplinary approach to treatment, including pharmacological treatment modalities such as analgesics and non-pharmacological management such as desensitization techniques and physical therapy. Critically, it is necessary to regularly follow up and perform proper clinical evaluation and screening to improve the quality of life for patients with CVG.