Evidence map›Paper›PMID 39439531›Full record

ReviewFrontiers in toxicology2024

New approach methodologies (NAMs) for the

Lynne T Haber, Mark A Bradley, Amanda N Buerger, Holger Behrsing, Sabina Burla, Phillip W Clapp, Scott Dotson, Casey Fisher, Keith R Genco, Francis H Kruszewski and 7 more

Abstract readReview
In one paragraph

Review in Frontiers in toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Frontiers in toxicology · 2026
    Article
  3. Article
  4. Readiness of theFrontiers in toxicology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Lynne T HaberRisk Science Center, Department of Environmental and Public Health Sciences, University of Cincinnati, Cincinnati, OH, United States.
Mark A BradleyRisk Science Center, Department of Environmental and Public Health Sciences, University of Cincinnati, Cincinnati, OH, United States.
Amanda N BuergerStantec ChemRisk, Cincinnati, OH, United States.
Holger BehrsingInstitute for In Vitro Sciences, Inc., Gaithersburg, MD, United States.
Sabina BurlaInvitrolize sarl, Belvaux, Luxembourg.
Phillip W ClappWake Forest Institute for Regenerative Medicine, Winston-Salem, NC, United States.
Scott DotsonInsight Exposure and Risk Sciences Group, Cincinnati, OH, United States.
Casey FisherEcolab, St. Paul, MN, United States.
Keith R GencoArkema Inc., King of Prussia, PA, United States.
Francis H KruszewskiAmerican Cleaning Institute®, Washington, DC, United States.
Shaun D McCulloughPublic Health and Integrated Toxicology Division, Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. EPA, Chapel Hill, NC, United States.
Kathryn E PageThe Clorox Company, Pleasanton, CA, United States.
Vivek PatelInstitute for In Vitro Sciences, Inc., Gaithersburg, MD, United States.
Nathan PechacekEcolab, St. Paul, MN, United States.
Clive RoperRoper Toxicology Consulting Limited, Edinburgh, United Kingdom.
Monita SharmaPETA Science Consortium International e.V, Stuttgart, Germany.
Annie M JarabekHealth and Environmental Effects Assessment Division, Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. EPA, Chapel Hill, NC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of

Indexed as

adverse outcome pathwayair-liquid interfacebest practicescleaning productsinhalation dosimetryin vitronew approach methodologiesrespiratory irritation

Identifiers

PMID39439531
PMCPMC11493779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.