Evidence map›Paper›PMID 39439468›Full record

ReviewInternational journal of medical sciences2024

Recent Progress of CircRNAs in Hematological Malignancies.

Ya-Bin Cui, Li-Jie Wang, Jin-Hui Xu, Hui-Jie Nan, Pei-Yao Yang, Jun-Wei Niu, Ming-Yue Shi, Yan-Liang Bai

Abstract readReview
In one paragraph

Review in International journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ya-Bin CuiDepartment of Hematology, Henan University People's Hospital and Henan Provincial People's Hospital, Zhengzhou 450003, P.R. China.
Li-Jie WangDepartment of Hematology, Henan University People's Hospital and Henan Provincial People's Hospital, Zhengzhou 450003, P.R. China.
Jin-Hui XuDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou 450003, P.R. China.
Hui-Jie NanDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou 450003, P.R. China.
Pei-Yao YangDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou 450003, P.R. China.
Jun-Wei NiuDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou 450003, P.R. China.
Ming-Yue ShiDepartment of Hematology, Zhengzhou University People's Hospital and Henan Provincial People's Hospital, Zhengzhou 450003, P.R. China.
Yan-Liang BaiDepartment of Hematology, Henan University People's Hospital and Henan Provincial People's Hospital, Zhengzhou 450003, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circular RNAs (circRNAs) are now recognized as key regulators in the epigenetic control of genetic expression, being involved in a wide range of cellular activities such as proliferation, differentiation, and apoptosis. Their unique closed-loop structure endows them with stability and resistance to exonuclease degradation, making them not only key regulatory molecules within the cell but also promising biomarkers for disease diagnosis and prognosis, particularly in hematological malignancies. This review comprehensively explores the role of circRNAs in the pathogenesis, progression, and therapeutic resistance of common hematological malignancies. Furthermore, the review delves into the prognostic significance of circRNAs, underscoring their potential in predicting disease outcomes and treatment response. Given their extensive involvement in cancer biology, circRNAs present a frontier for novel therapeutic strategies.

Indexed as

Biomarkers, TumorHematologic NeoplasmsRNA, CircularEpigenesis, GeneticGene Expression Regulation, NeoplasticHumansPrognosisBiomarkers, TumorRNA, CircularcircRNAhematological malignanciesleukemialymphomamultiple myelomaresistance

Identifiers

PMID39439468
PMCPMC11492881

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.