Trial reportInternational journal of medical sciences2024
Effect of Remimazolam on the Incidence of Intraoperative Hypothermia Compared with Inhalation Anesthetics in Patients Undergoing Endoscopic Nasal Surgery: A Prospective Randomized Controlled Trial.
Trial report in International journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Comparison of Remimazolam and Sevoflurane on Perioperative Body Temperature Changes in Older Patients Undergoing Transurethral Resection of Prostate or Bladder Tumors Under General Anesthesia: A Randomized Prospective Clinical Trial.Clinical interventions in aging · 2025Trial
- Various machine learning prediction models for short-term postoperative prognosis of colorectal cancer based on intraoperative hypothermia.American journal of cancer research · 2026Article
- Comparative effects of remimazolam and propofol on intraoperative redistribution hypothermia in urologic surgery: a retrospective propensity-matched cohort study.International journal of medical sciences · 2026Observational
- Reevaluating anesthesia maintenance strategies to prevent intraoperative hypothermia in hip arthroplasty: a randomized controlled trial.American journal of translational research · 2026Article
- Effect of airway management method on hypothermia in patients undergoing laparoscopic gynecologic surgery: tracheal intubation, supreme laryngeal mask, and i-gel laryngeal mask.American journal of translational research · 2025Article
- Article
- Construction and validation of a predictive model for hypothermia complication during endoscopic thyroidectomy for thyroid cancer.Frontiers in molecular biosciences · 2025Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRemimazolam is an ultrashort-acting benzodiazepine that is increasingly used for its efficacy in anesthesia induction and maintenance. However, limited research has explored its impact on intraoperative hypothermia compared to that of traditional inhalation anesthetics. This study aimed to compare the incidence of hypothermia during endoscopic nasal surgery when using remimazolam for maintenance anesthesia versus using inhalation anesthetics.
methodsThis prospective study included 70 patients who underwent endoscopic nasal surgery under general anesthesia. The patients were randomly assigned to one of two groups: the inhalation anesthetic (IA) group (n=35), in which desflurane and nitrous oxide were administered, and the remimazolam (R) group (n=35), in which remimazolam and remifentanil were administered for anesthesia maintenance. The primary outcome was the incidence of intraoperative hypothermia, defined as an esophageal temperature below 36 °C during anesthesia.
resultsThe incidence of intraoperative hypothermia was significantly higher in the R group than in the IA group (P = 0.014). Furthermore, the temperature at the end of the surgery was significantly lower in the R group than in the IA group (P = 0.006). Additionally, the use of warming devices after surgery was more frequent in the R group than in the IA group (P = 0.047).
conclusionsThese findings suggest that the use of remimazolam for maintenance anesthesia during endoscopic nasal surgery increases the risk of intraoperative hypothermia compared to the use of inhalation anesthetics. This highlights the importance of temperature monitoring in patients receiving remimazolam to minimize the adverse outcomes associated with hypothermia during surgery.
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