Evidence map›Paper›PMID 39439362›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Effectiveness of psychological therapies for depression and anxiety in atypical dementia.

Celine El Baou, Rob Saunders, Joshua E J Buckman, Marcus Richards, Claudia Cooper, Natalie L Marchant, Roopal Desai, Georgia Bell, Caroline Fearn, Stephen Pilling and 6 more

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Effectiveness of psychological therapies for depression and anxiety in atypical dementia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Celine El BaouAdapt Lab, Research Department of Clinical, Educational and Health Psychology, UCL London, London, UK.ORCID 0000-0002-7212-1835
Rob SaundersAdapt Lab, Research Department of Clinical, Educational and Health Psychology, UCL London, London, UK.
Joshua E J BuckmanCentre for Outcomes Research and Effectiveness, Research Department of Clinical, Educational and Health Psychology, UCL, London, UK.
Marcus RichardsMRC Unit for Lifelong Health and Ageing at UCL, UCL, London, UK.
Claudia CooperCentre for Psychiatry and Mental Health, Wolfson Institute of Population Health, Queen Mary University, London, UK.
Natalie L MarchantDivision of Psychiatry, UCL, London, UK.
Roopal DesaiAdapt Lab, Research Department of Clinical, Educational and Health Psychology, UCL London, London, UK.
Georgia BellAdapt Lab, Research Department of Clinical, Educational and Health Psychology, UCL London, London, UK.
Caroline FearnAdapt Lab, Research Department of Clinical, Educational and Health Psychology, UCL London, London, UK.
Stephen PillingCentre for Outcomes Research and Effectiveness, Research Department of Clinical, Educational and Health Psychology, UCL, London, UK.
Nikki ZimmermannDementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.
Val MansfieldDementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.
Sebastian CrutchDementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.
Emilie BrotherhoodDementia Research Centre, UCL Queen Square Institute of Neurology, London, UK.
Amber JohnAdapt Lab, Research Department of Clinical, Educational and Health Psychology, UCL London, London, UK.
Joshua StottAdapt Lab, Research Department of Clinical, Educational and Health Psychology, UCL London, London, UK.

Funding

Alzheimer's Research UK Research Fellowship ARUK-RF2021B-007Alzheimer's Society AS-PG-18-013Alzheimer's Society Senior Fellowship AS-SF-15B-002Medical Research CouncilMedical Research Council MC_UU_00019/1National Institute for Health and Care Research (NIHR) Dementia and Neurodegeneration Policy Research Unit NIHR205009National Institute for Health and Care Research (NIHR) Dementia and Neurodegeneration Policy Research Unit NIHR206110National Institute for Health and Care Research, Programme Grants for Applied Research NIHR203680University College London Hospitals NHS Foundation Trust and the National Institute for Health and Care Research Biomedical Research Centre
6 · The paper itself

Abstract

introductionPeople with dementia may benefit from psychological therapies for depression or anxiety, but evidence of their effectiveness in atypical dementia is limited.

methodsUsing electronic health-care records of > 2 million people who attended psychological therapy services in England between 2012 and 2019, we examined pre-post therapy symptom changes and compared therapy outcomes among 523 people with atypical dementia, a matched cohort without dementia, and 1157 people with typical dementia.

resultsPeople with atypical dementia experienced reductions in depression (Cohen d = -0.92 [-1.05 to -0.79]) and anxiety (d = -0.85 [-0.98 to -0.73]) symptoms. They had similar odds of improvement than people with typical dementia (odds ratio [OR] = 1.07, 95% confidence interval [CI]: 0.85 to 1.34), but lower odds than people living without dementia (OR = 0.70, 95% CI: 0.53 to 0.91). Reasons for discharge were similar between all groups. DISCUSSION: People with atypical dementia may benefit from primary care psychological therapies, but further research is needed to explore necessary adaptations. HIGHLIGHTS: Talking therapies for depression and anxiety may be beneficial for people with atypical dementia. Being younger and having a lower socioeconomic background are associated with poorer outcomes. Receiving more treatment sessions and shorter waiting times are associated with better outcomes.

Indexed as

AnxietyDementiaDepressionAgedAged, 80 and overEnglandFemaleHumansMalePsychotherapyTreatment Outcomeanxietyatypical dementiadepressionprimary carepsychological therapies

Identifiers

PMID39439362
PMCPMC11667512

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.