Evidence map›Paper›PMID 39439236›Full record

ArticleGut microbes

Fecal samples and rectal swabs adequately reflect the human colonic luminal microbiota.

Julia Rode, Linnea Brengesjö Johnson, Julia König, Ignacio Rangel, Lars Engstrand, Dirk Repsilber, Robert J Brummer

Abstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Strengths and limitations ofGut microbes reports · 2026
    Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julia RodeSchool of Medical Sciences, Faculty of Medicine and Health, Nutrition-Gut-Brain Interactions Research Centre, Örebro University, Örebro, Sweden.ORCID 0000-0001-9402-4756
Linnea Brengesjö JohnsonSchool of Medical Sciences, Faculty of Medicine and Health, Nutrition-Gut-Brain Interactions Research Centre, Örebro University, Örebro, Sweden.
Julia KönigSchool of Medical Sciences, Faculty of Medicine and Health, Nutrition-Gut-Brain Interactions Research Centre, Örebro University, Örebro, Sweden.
Ignacio RangelSchool of Medical Sciences, Faculty of Medicine and Health, Nutrition-Gut-Brain Interactions Research Centre, Örebro University, Örebro, Sweden.
Lars EngstrandCentre for Translational Microbiome Research, Dept Microbiology, Tumor and Cell Biology, Karolinska Institute, Solna, Sweden.
Dirk RepsilberSchool of Medical Sciences, Faculty of Medicine and Health, Nutrition-Gut-Brain Interactions Research Centre, Örebro University, Örebro, Sweden.
Robert J BrummerSchool of Medical Sciences, Faculty of Medicine and Health, Nutrition-Gut-Brain Interactions Research Centre, Örebro University, Örebro, Sweden.

Funding

Mag-TarmFonden, Swedish Gastroenterology Society Swedish Knowledge Foundation 20230004-H-01
6 · The paper itself

Abstract

The appropriateness of the fecal microbiota to adequately reflect the gut microbiota composition from more difficult to access luminal content at different colonic locations has been debated. Here, in a healthy population, luminal samples were collected from terminal ileum to rectum using an unique sampling technique without the need of prior bowel cleansing/preparation. Rectal swabs were collected immediately prior colonoscopy by an experienced physician, and fecal samples were collected at home by the participants themselves. Microbiota composition was evaluated as relative abundance, α-diversity and Bray-Curtis dissimilarities. Our data suggest that fecal samples and rectal swabs present noninvasive, easily accessible, low-cost sampling tools that are accurate proxies to characterize luminal large intestinal microbiota composition.

Indexed as

ColonFecesGastrointestinal MicrobiomeRectumSpecimen HandlingAdultBacteriaColonoscopyFemaleHumansMaleMiddle AgedYoung Adultaspirationfecesgut microbiomeGut microbiotaintraluminalrectalsampling technique

Identifiers

PMID39439236
PMCPMC11508938

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.