Evidence map›Paper›PMID 39439216›Full record

ArticleNeuropsychopharmacology reports2024

Changes in interoception before and after treatment in patients with alcohol use disorder.

Chika Shimohara, Ariyuki Kagaya, Tomoyuki Akita, Ryotaro Tsukue, Atsushi Shimohara, Maro G Machizawa, Shigeto Yamawaki, Junko Tanaka, Hitoshi Okamura

Abstract read
In one paragraph

Article in Neuropsychopharmacology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chika ShimoharaDepartment of Psychosocial Rehabilitation, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Ariyuki KagayaSenogawa Hospital, Senogawa Medical Corporation, Hiroshima, Japan.
Tomoyuki AkitaDepartment of Epidemiology, Infectious Disease Control and Prevention, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Ryotaro TsukueSenogawa Hospital, Senogawa Medical Corporation, Hiroshima, Japan.
Atsushi ShimoharaYokogawa Ekimae Clinic, Senogawa Medical Corporation, Hiroshima, Japan.
Maro G MachizawaCenter for Brain, Mind & KANSEI Sciences Research, Hiroshima University, Hiroshima, Japan.ORCID 0000-0002-5727-1421
Shigeto YamawakiCenter for Brain, Mind & KANSEI Sciences Research, Hiroshima University, Hiroshima, Japan.
Junko TanakaDepartment of Epidemiology, Infectious Disease Control and Prevention, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Hitoshi OkamuraDepartment of Psychosocial Rehabilitation, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.ORCID 0000-0002-5629-9342

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo investigate the factors associated with interoception in patients with alcohol use disorder and determine whether treatment causes changes in their interoception.

methodsThe Body Perception Questionnaire-Body Awareness ultra-short version Japanese version (BPQ-BAVSF-J) was used to measure interoception in 50 alcohol-dependent participants (27 in the inpatient group and 23 in the outpatient group). The BPQ-BAVSF-J was administered and data on aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transpeptidase (γ-GTP), mean corpuscular volume, platelet count, and Fib-4 index were extracted at admission and immediately before discharge for the inpatient group and at the first outpatient visit and approximately 3 months after the visit for the outpatient group.

resultsThe mean age of the 50 participants was 51.0 ± 12.3 years. Significant associations were found between the BPQ-BAVSF-J and Fib-4 index and AST. The BPQ-BAVSF-J score significantly decreased at discharge in the inpatient group. AST, ALT, γ-GTP, and Fib-4 index of liver function were also significantly lower at discharge. In contrast, in the outpatient group, there were no significant changes in the BPQ-BAVSF-J score, AST level, ALT level, γ-GTP level, and Fib-4 index between at the first outpatient visit and approximately 3 months after the visit.

conclusionsInteroception in patients with alcohol use disorder increased with worsening liver function and decreased with improvement in liver function owing to treatment. This suggests that the BPQ-BAVSF-J score, an easily accessible scale, may be used to detect early deterioration of liver function through regular administration.

Indexed as

AlcoholismInteroceptionAdultAlanine TransaminaseAspartate AminotransferasesFemalegamma-GlutamyltransferaseHumansMaleMiddle AgedSurveys and QuestionnairesAlanine TransaminaseAspartate Aminotransferasesgamma-Glutamyltransferasealcohol use disorderBPQ‐BAVSFinteroceptionliver function

Identifiers

PMID39439216
PMCPMC11609739

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.