Evidence map›Paper›PMID 39438760›Full record

ArticleScientific reports2024

Global tilt angle in spinal alignment of asymptomatic older women with low bone mass.

Ping-Chiao Tsai, Ssu-Hsien Lee, Yu-Chieh Chiu, Wen-Tien Wu, Ru-Ping Lee, Tzai-Chiu Yu, Ing-Ho Chen, Jen-Hung Wang, Kuang-Ting Yeh

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ping-Chiao TsaiSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Ssu-Hsien LeeSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Yu-Chieh ChiuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Wen-Tien WuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Ru-Ping LeeInstitute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.
Tzai-Chiu YuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Ing-Ho ChenSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Jen-Hung WangDepartment of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Kuang-Ting YehSchool of Medicine, Tzu Chi University, Hualien, Taiwan. micrograft@tzuchi.com.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the relationship between sagittal spinal alignment and musculoskeletal health in older women, particularly those exhibiting diminished bone density without apparent symptoms. The study assessed the impact of global tilt (GT) and the presence of coronal malalignment on spinal health. The research involved 165 asymptomatic older women with an average age of 68.91 ± 7.25 years and average body mass index of 24.26 ± 3.66 kg/m². Comprehensive standing anteroposterior and lateral spine radiographs were used for assessment. Through multivariate linear regression analysis, the study identified significant correlations between increased GT angles and various factors, including coronal malalignment, the C7 slope, and pelvic incidence. This led to the formulation of a predictive GT model: GT = -9.79 + 0.06 × menopausal period + 0.19 × body mass index (BMI)- 0.81 × average T score - 0.11 × grip strength + 3.03 × (presence of coronal malalignment) + 0.08 × sagittal vertical axis (SVA) + 0.12 × C7 slope - 0.35 × upper lumbar lordosis (ULL) - 0.43 × lower lumbar lordosis (LLL) + 0.70 × pelvic incidence (PI), with an adjusted R² of 0.816. The study findings highlight the prevalence of coronal malalignment in this demographic and its significant associations with critical spinal parameters. The proposed GT predictive model may enable development of personalized treatment plans for older women with low bone mass.

Indexed as

Bone DensityAgedAged, 80 and overBody Mass IndexFemaleHumansLordosisLumbar VertebraeMiddle AgedRadiographySpineAsymptomatic woman with low bone massC7 slopeCoronal malalignmentGlobal tilt angleOlderSagittal alignment

Identifiers

PMID39438760
PMCPMC11496500

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.