Evidence map›Paper›PMID 39438501›Full record

ArticleScientific reports2024

Centrally mediated responses to NMES are influenced by muscle group and stimulation parameters.

Timothée Popesco, Quentin Gardet, Jonathan Bossard, Nicola A Maffiuletti, Nicolas Place

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Role of Functional Electrical Stimulation in Stroke Rehabilitation: A Preliminary Study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Timothée PopescoInstitute of Sport Sciences, University of Lausanne, Lausanne, 1015, Switzerland.
Quentin GardetInstitute of Sport Sciences, University of Lausanne, Lausanne, 1015, Switzerland.
Jonathan BossardInstitute of Sport Sciences, University of Lausanne, Lausanne, 1015, Switzerland.
Nicola A MaffiulettiHuman Performance Lab, Schulthess Clinic, Zurich, Switzerland.
Nicolas PlaceInstitute of Sport Sciences, University of Lausanne, Lausanne, 1015, Switzerland. nicolas.place@unil.ch.

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 32003B_204364 / 1
6 · The paper itself

Abstract

Wide-pulse high-frequency neuromuscular electrical stimulation (WPHF NMES) can generate a progressive increase in tetanic force through reflexive recruitment of motor units, called extra force. This phenomenon has previously been observed on different muscle groups, but little is known on potential inter-muscle differences. We compared extra force and sustained electromyographic (EMG) activity induced by NMES between plantar flexors, knee extensors, elbow flexors and within muscle groups using pulse durations of 0.2, 1 and 2 ms and stimulation frequencies of 20, 50, 100 and 147 Hz. Extra force production and sustained EMG activity were higher for plantar flexors compared to elbow flexors at all tested parameters (except 0.2 ms for extra force). When compared to elbow flexors, extra force of the knee extensors was only higher at 100 Hz and with 1 ms while sustained EMG activity was higher at all frequencies with pulse durations of 0.2 and 2 ms. Peripheral nerve architecture as well as muscle typology and function could influence the occurrence and magnitude of centrally-mediated responses to NMES. The present findings suggest that the use of wide-pulse high-frequency NMES to promote reflexive recruitment seems to be more pertinent for lower limb muscles, plantar flexors in particular.

Indexed as

Electric StimulationElectromyographyMuscle, SkeletalAdultFemaleHumansKneeMaleMotor NeuronsMuscle ContractionRecruitment, NeurophysiologicalYoung AdultExtra forceInter-muscle comparisonNMESPulse durationStimulation frequencySustained EMG activity

Identifiers

PMID39438501
PMCPMC11496505

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.