ArticleNature communications2024
Loss of HIV candidate vaccine efficacy in male macaques by mucosal nanoparticle immunization rescued by V2-specific response.
Abstract read
In one paragraph
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Preferential engagement of the anti-inflammatory ATP/adenosine axis by HIV vaccine candidate with V1-deleted envelope in male rhesus macaques.Cell reports. Medicine · 2026Article
- Sustained mucosal delivery of SAMT-247 via an intravaginal ring reduces the risk of SIVCell reports. Medicine · 2026Article
- Friend or foe: divergent immunomodulatory effects of metabolites derived from the virucidal zinc finger inhibitor SAMT-247.Frontiers in immunology · 2026Article
- ALFQ adjuvanted HIV-1 envelope protein vaccination elicits durable functional antibody and cellular responses in nonhuman primates.NPJ vaccines · 2025Article
- HIV vaccine candidate ΔV1gp120 formulated in ALFQA adjuvant augments mucosal immunity in female macaques.Nature communications · 2025Article
- Immunogenicity and protection mediated by dmLT and alum adjuvants for an HIV-1 vaccine.Frontiers in immunology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors.
Mohammad Arif Rahman *Animal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-6120-8943
Massimiliano Bissa *Animal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0003-3455-3992
Hanna Scinto *Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Savannah E HoweVaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Sarkis SarkisAnimal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Zhong-Min MaCalifornia National Primate Research Center, University of California, Davis, Davis, USA.ORCID 0000-0003-3713-7337
Anna GutowskaAnimal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-9873-6432
Xunqing JiangDepartment of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.
Christina C LuoDepartment of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.ORCID 0000-0001-9872-7432
Luca SchifanellaAnimal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Ramona MolesAnimal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Isabela Silva de CastroAnimal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Shraddha BasuUnited States Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
Kombo F N'guessanUnited States Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
LaTonya D WilliamsCenter for Human Systems Immunology, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
Manuel Becerra-FloresNew York University School of Medicine, NYU Langone Health, New York, NY, USA.
Melvin N DosterAnimal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Tanya HoangVaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Hyoyoung Choo-WosobaOffice of Collaborative Biostatistics, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Emmanuel WoodeAnimal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Yongjun SuiVaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-1568-4607
Georgia D TomarasCenter for Human Systems Immunology, Department of Surgery, Duke University School of Medicine, Durham, NC, USA.
Dominic Paquin-ProulxUnited States Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID 0000-0003-1407-3414
Mangala RaoUnited States Military HIV Research Program, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD, USA.ORCID 0000-0001-9553-4969
James D TaltonAlchem Laboratories Corporation, Alachua, FL, USA.
Xiang-Peng KongDepartment of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.
Susan Zolla-PaznerDepartment of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, NY, New York, USA.ORCID 0000-0002-0750-2666
Timothy CardozoNew York University School of Medicine, NYU Langone Health, New York, NY, USA.ORCID 0000-0002-0643-4497
Genoveffa FranchiniAnimal Models and Retroviral Vaccines Section, Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. franchig@mail.nih.gov.ORCID 0000-0003-2851-6589
Jay A BerzofskyVaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. berzofsj@mail.nih.gov.ORCID 0000-0002-0342-3194
Funding
Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI Nwora Lance Okeke · 2005 to 2026
$50.5MNonhuman Primate Reagent ResourceU24AI126683 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Diogo Magnani · 2016 to 2026
$20.1MResource for Nonhuman Primate Cell Depleting AntibodiesR24OD010976 · OD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ENGELMAN, KATHLEEN, MAGNANI, DIOGO · 2012 to 2019
$4.7MCombined cocaine and HIV vaccineDP1DA036478 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CARDOZO, TIMOTHY J · 2013 to 2017
$4.7MStructure and immunogenicity of novel trimeric HIV-1 Env immunogensR01AI145655 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI KONG, XIANGPENG · 2019 to 2023
$4.7MNIAID NIH HHS HHSN272201100016CNIAID NIH HHS HHSN272201300031CNIAID NIH HHS P30 AI064518NIAID NIH HHS R01 AI145655NIAID NIH HHS U24 AI126683NIDA NIH HHS DP1 DA036478NIH HHS R24 OD010976
Abstract
Systemic vaccination of macaques with V1-deleted (ΔV1) envelope immunogens reduce the risk of SIV
Indexed as
AIDS VaccinesImmunity, MucosalNanoparticlesAnimalsDendritic CellsHIV InfectionsImmunizationMacaca mulattaMaleSAIDS VaccinesSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusVaccinationVaccine EfficacyAIDS VaccinesSAIDS Vaccines
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.