ArticleNature communications2024
Integration of rate and phase codes by hippocampal cell-assemblies supports flexible encoding of spatiotemporal context.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- VTA-forebrain connectivity moderates adaptive behavior.Brain structure & function · 2026Review
- dCA1 cells encode and update contextual place preference.Frontiers in systems neuroscience · 2026Article
- Out of the single-neuron straitjacket: Neurons within assemblies change selectivity and their reconfiguration underlies dynamic coding.The Journal of physiology · 2025Article
- Integration of rate and phase codes by hippocampal cell-assemblies supports flexible encoding of spatiotemporal context.Nature communications · 2024Article
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Authors and funding
7 authors.
Funding
Abstract
Spatial information is encoded by location-dependent hippocampal place cell firing rates and sub-second, rhythmic entrainment of spike times. These rate and temporal codes have primarily been characterized in low-dimensional environments under limited cognitive demands; but how is coding configured in complex environments when individual place cells signal several locations, individual locations contribute to multiple routes and functional demands vary? Quantifying CA1 population dynamics of male rats during a decision-making task, here we show that the phase of individual place cells' spikes relative to the local theta rhythm shifts to differentiate activity in different place fields. Theta phase coding also disambiguates repeated visits to the same location during different routes, particularly preceding spatial decisions. Using unsupervised detection of cell assemblies alongside theoretical simulation, we show that integrating rate and phase coding mechanisms dynamically recruits units to different assemblies, generating spiking sequences that disambiguate episodes of experience and multiplexing spatial information with cognitive context.
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Registered trials
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