SynthesisThe British journal of clinical psychology2025
Intolerance of uncertainty and psychosis: A systematic review.
Synthesis in The British journal of clinical psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intolerance of uncertainty and psychosis: A systematic review.The British journal of clinical psychology · 2025Pooled it
- Paranoid Ideation in Gay Men: The Roles of Psychological Emptiness, Identity Loss, Loneliness, and Identity Resilience.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Intolerance of uncertainty, paranoia, and prodromal symptoms: Comparisons between a schizophrenia spectrum disorder, anxiety disorder and non-clinical sample.Psychology and psychotherapy · 2025Article
- Cross-cultural validation of the Chinese version of Disorder-Specific Intolerance of Uncertainty (DSIU): psychometric properties in female college students with premenstrual syndrome (PMS).BMC psychiatry · 2025Article
- Fear learning and generalization in youth with early-stage transdiagnostic psychiatric symptoms and the impact of acute exercise.Frontiers in psychiatry · 2025Article
- The cumulative social adversity hypothesis of psychosis: Intolerance of uncertainty and aberrant salience mediate the association between humiliation and psychotic-like experiences.Frontiers in psychiatry · 2025Article
- An Examination of Intolerance of Uncertainty in Schizophrenia.Clinical psychology & psychotherapyArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIntolerance of uncertainty, the tendency to interpret and react negatively to uncertainty, is a transdiagnostic risk factor for anxiety, depression and eating-related disorders. Given the high comorbidity between anxiety, depression and schizophrenia-spectrum diagnoses (SSDs), there is potential for intolerance of uncertainty to play a role in modulating psychosis symptoms. To address this gap in our understanding, we conducted the first prospectively registered systematic review on intolerance of uncertainty and psychotic symptoms in both people with SSDs and in the general population.
methodsFour databases were searched (PsycINFO, Medline, Web of Science and PubMed), which identified ten studies with a total of 1503 participants that measured intolerance of uncertainty and psychosis symptoms.
resultsKey findings suggest the following: (1) Intolerance of uncertainty was associated with total negative psychotic symptoms with small-medium effect sizes; (2) intolerance of uncertainty was higher in individuals with an 'at-risk' mental state for psychosis compared to controls; (3) higher intolerance of uncertainty was associated with more individual psychotic symptoms related to delusions and paranoia within clinical and nonclinical samples; and (4) there was mixed evidence for a relationship between intolerance of uncertainty and auditory hallucinations and intolerance of uncertainty and total positive symptoms in clinical samples.
conclusionsOverall, these findings highlight that intolerance of uncertainty may be an important transdiagnostic dimension and potential treatment target for psychotic symptoms such as delusions and paranoia in people with SSDs.
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