Evidence map›Paper›PMID 39438414›Full record

ArticleDigestive diseases and sciences2024

Association Between Body Composition Measured by Artificial Intelligence and Long-Term Sequelae After Acute Pancreatitis.

Pedro Cortés, Tyler Mistretta, Brittany Jackson, Caroline G Olson, Ahmed M Salih, Fernando F Stancampiano, Panagiotis Korfiatis, Jason R Klug, Dana M Harris, JDan Echols and 6 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Digestive diseases and sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Pedro CortésDivision of Gastroenterology and Hepatology, University of Washington, Seattle, WA, USA.
Tyler MistrettaDivision of Medicine, Mayo Clinic, Jacksonville, FL, USA.
Brittany JacksonDivision of Medicine, Mayo Clinic, Jacksonville, FL, USA.
Caroline G OlsonDivision of Medicine, Mayo Clinic, Jacksonville, FL, USA.
Ahmed M SalihDivision of Internal Medicine, Indiana University, Indianapolis, IN, USA.
Fernando F StancampianoDivision of Medicine, Mayo Clinic, Jacksonville, FL, USA.
Panagiotis KorfiatisDivision of Radiology, Mayo Clinic, Rochester, MN, USA.
Jason R KlugDivision of Radiology, Mayo Clinic, Rochester, MN, USA.
Dana M HarrisDivision of Medicine, Mayo Clinic, Jacksonville, FL, USA.
JDan EcholsDivision of Medicine, Mayo Clinic, Jacksonville, FL, USA.
Rickey E CarterDigital Innovation Lab, Mayo Clinic, Jacksonville, FL, USA.
Baoan JiDivision of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
Heather D HardwayDigital Innovation Lab, Mayo Clinic, Jacksonville, FL, USA.
Michael B WallaceDivision of Gastroenterology and Hepatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Vivek KumbhariDivision of Gastroenterology and Hepatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
Yan BiDivision of Gastroenterology and Hepatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA. bi.yan@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThe clinical utility of body composition in the development of complications of acute pancreatitis (AP) remains unclear. We aimed to describe the associations between body composition and the recurrence of AP.

methodsWe performed a retrospective study of patients hospitalized with AP at three tertiary care centers. Patients with computer tomography (CT) imaging of the abdomen at admission were included. A previously validated and fully automated abdominal segmentation algorithm was used for body composition analysis. Hospitalization for a recurrent episode of AP was the primary endpoint. Secondary endpoints included the development of chronic pancreatitis (CP) or diabetes mellitus (DM) in patients who were evaluated. Cox Proportional Hazards regression was used.

resultsFrom a total of 347 patients, 89 (25.6%) were hospitalized for recurrent AP (median time: 219 days). Thirty-four of 112 patients (30.4%) developed CP (median time: 311 days) and 22 of 88 (25.0%) developed DM (median time: 1104 days). After adjusting for age, male sex, first episode of AP, BUN, and severity of AP, we found that obesity, body mass index, alcohol pancreatitis, and gallstone pancreatitis were significantly associated with a recurrent episode of AP. Body composition was not associated with recurrent AP. In unadjusted analysis, subcutaneous adipose tissue (SAT) (HR 0.87 per 10 cm

conclusionBody composition was not associated with having a recurrent AP. At follow-up, 30% and 25% of evaluated patients developed CP and DM, respectively. A higher SAT and IMAT were associated with a lower incidence of CP and higher incidence of DM, respectively.

Indexed as

Artificial IntelligenceBody CompositionPancreatitisRecurrenceAcute DiseaseAdultAgedDiabetes MellitusFemaleHumansMaleMiddle AgedPancreatitis, ChronicRetrospective StudiesRisk FactorsTomography, X-Ray ComputedArtificial intelligenceBody compositionChronic pancreatitisRecurrent acute pancreatitis

Identifiers

PMID39438414

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.