Evidence map›Paper›PMID 39438353›Full record

ArticleMetabolomics : Official journal of the Metabolomic Society2024

BW312 Hordeum vulgare semi-dwarf mutant exhibits a shifted metabolic profile towards pathogen resistance.

Richard Rigo, Julie Zumsteg, Hubert Schaller, Thierry Barchietto, Sergej Buchet, Dimitri Heintz, Claire Villette

Abstract read
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Article in Metabolomics : Official journal of the Metabolomic Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Richard RigoBIOtransfer, 41 Rue Emile Zola, 93100, Montreuil, France.
Julie ZumstegPlant Imaging & Mass Spectrometry (PIMS), Institut de Biologie Moléculaire Des Plantes, CNRS, Université de Strasbourg, 12 Rue du Général Zimmer, 67084, Strasbourg, France.
Hubert SchallerPlant Isoprenoid Biology (PIB), Institut de Biologie Moléculaire Des Plantes, CNRS, Université de Strasbourg, 12 Rue du Général Zimmer, 67084, Strasbourg, France.
Thierry BarchiettoBIOtransfer, 41 Rue Emile Zola, 93100, Montreuil, France.
Sergej BuchetBIOtransfer, 41 Rue Emile Zola, 93100, Montreuil, France.
Dimitri HeintzPlant Imaging & Mass Spectrometry (PIMS), Institut de Biologie Moléculaire Des Plantes, CNRS, Université de Strasbourg, 12 Rue du Général Zimmer, 67084, Strasbourg, France.
Claire VillettePlant Imaging & Mass Spectrometry (PIMS), Institut de Biologie Moléculaire Des Plantes, CNRS, Université de Strasbourg, 12 Rue du Général Zimmer, 67084, Strasbourg, France. claire.villette@ibmp-cnrs.unistra.fr.ORCID http://orcid.org/0000-0003-2564-5529

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPlant hormonal mutants, which do not produce or are insensitive to hormones, are often affected in their growth and development, but other metabolic rearrangements might be involved. A trade-off between growth and stress response is necessary for the plant survival.

objectivesHere, we explore the metabolic profile and the pathogen resistance of a brassinosteroid-insensitive Hordeum vulgare L. semi-dwarf mutant, BW312.

methodsWe investigate BW312 metabolism through a chemical enrichment analysis, confirming a shifted metabolic profile towards pathogen resistance. The effective pathogen resistance of the mutant was tested in presence of Pyrenophora teres and Fusarium graminearum.

resultsFour compound families were increased in the mutant (pyrrolidines, basic amino acids, alkaloids, monounsaturated fatty acids), while two compound families were decreased (pyrrolidinones, anthocyanins). Dipeptides were also altered (increased and decreased). BW312 displayed a better resistance to Pyrenophora teres in the earliest stage of infection with a 21.5% decrease of the lesion length 10 days after infection. BW312 also exhibited a reduced lesion length (43.3%) and a reduced browning of the lesions (55.5%) when exposed to Fusarium graminearum at the seedling stage.

conclusionThe observed metabolomic shift strongly suggests that the BW312 semi-dwarf mutant is in a primed state, resulting in a standby state of alertness to pathogens.

Indexed as

Disease ResistanceFusariumHordeumMutationPlant DiseasesAscomycotaMetabolomeFusarium graminearumHordeum vulgareNon-targeted metabolomicsPathogen resistancePyrenophora teres

Identifiers

PMID39438353

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.