Evidence map›Paper›PMID 39438133›Full record

ArticleJournal of neurointerventional surgery2025

Ultra-high resolution CT angiography for the assessment of intracranial stents and flow diverters using photon counting detector CT.

Riccardo Ludovichetti, Dunja Gorup, Mikos Krepuska, Sebastian Winklhofer, Patrick Thurner, Jawid Madjidyar, Thomas Flohr, Marco Piccirelli, Lars Michels, Hatem Alkadhi and 3 more

Abstract read
In one paragraph

Article in Journal of neurointerventional surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Riccardo Ludovichetti *Department of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-6125-005X
Dunja Gorup *Department of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Mikos KrepuskaDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Sebastian WinklhoferDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Patrick ThurnerDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0003-3966-5520
Jawid MadjidyarDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Thomas FlohrDepartment of Diagnostic and Interventional Radiology, University of Zurich, Zurich, Switzerland.
Marco PiccirelliDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Lars MichelsDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Hatem AlkadhiDepartment of Diagnostic and Interventional Radiology, University of Zurich, Zurich, Switzerland.
Victor MergenDepartment of Diagnostic and Interventional Radiology, University of Zurich, Zurich, Switzerland.
Zsolt KulcsarDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland.
Tilman SchubertDepartment of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, Zurich, Switzerland tilman.schubert@usz.ch.ORCID http://orcid.org/0000-0003-2373-5870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe patency of intracranial stents may not be reliably assessed with either CT angiography or MR angiography due to imaging artifacts. We investigated the potential of ultra-high resolution CT angiography using a photon counting detector (PCD) CT to address this limitation by optimizing scanning and reconstruction parameters.

methodsA phantom with different flow diverters was used to optimize PCD-CT reconstruction parameters, followed by imaging of 14 patients with intracranial stents using PCD-CT. Images were reconstructed using three kernels based on the phantom results (Hv56, Hv64, and Hv72; Hv=head vascular) and one kernel to virtually match the resolution of standard CT angiography (Hv40). Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) measurements were calculated. Subjective image quality and diagnostic confidence (DC) were assessed using a five point visual grading scale (5=best, 1=worst) and a three point grading scale (1=best, 3=worst), respectively, by two independent neuroradiologists.

resultsPhantom images demonstrated the highest image quality across dose levels for 0.2 mm reconstructions with Hv56 (4.5), Hv64 (5), and Hv72 (5). In patient images, SNR and CNR decreased significantly with increasing kernel sharpness compared with control parameters. All reconstructions showed significantly higher image quality and DC compared with the control reconstruction with Hv40 kernel (P<0.001), with both image quality and DC being highest with Hv64 (0.2 mm) and Hv72 (0.2 mm) reconstructions.

conclusionUltra-high resolution PDC-CT angiography provides excellent visualization of intracranial stents, with optimal reconstructions using the Hv64 and the Hv72 kernels at 0.2 mm. REGISTRATION: BASEC 2021-00343.

Indexed as

Cerebral AngiographyComputed Tomography AngiographyStentsAgedFemaleHumansMaleMiddle AgedPhantoms, ImagingSignal-To-Noise RatioCT AngiographyFlow DiverterStent

Identifiers

PMID39438133
PMCPMC12573315

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.