Evidence map›Paper›PMID 39437758›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2024

Longitudinal microcomputed tomography detects onset and progression of pulmonary fibrosis in conditional

Dominik H W Leitz, Philip Konietzke, Willi L Wagner, Mara Mertiny, Claudia Benke, Thomas Schneider, Rory E Morty, Christian Dullin, Wolfram Stiller, Hans-Ulrich Kauczor and 3 more

Abstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Dominik H W LeitzDepartment of Pediatric Respiratory Medicine, Immunology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-0610-9088
Philip KonietzkeTranslational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
Willi L WagnerTranslational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
Mara MertinyTranslational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
Claudia BenkeTranslational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.ORCID 0009-0000-6614-0848
Thomas SchneiderDepartment of Diagnostic and Interventional Radiology, University Hospital Heidelberg, Heidelberg, Germany.ORCID 0000-0002-1456-980X
Rory E MortyTranslational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.ORCID 0000-0003-0833-9749
Christian DullinTranslational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
Wolfram StillerTranslational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.ORCID 0000-0001-9951-6020
Hans-Ulrich KauczorTranslational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.
Marcus A MallDepartment of Pediatric Respiratory Medicine, Immunology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-4057-2199
Julia DuerrDepartment of Pediatric Respiratory Medicine, Immunology and Intensive Care Medicine, Charité - Universitätsmedizin Berlin, Berlin, Germany.ORCID 0000-0002-4862-9487
Mark O WielpützTranslational Lung Research Center Heidelberg (TLRC), German Center for Lung Research (DZL), Heidelberg, Germany.ORCID 0000-0001-6962-037X

Funding

Bundesministerium für Bildung und Forschung (BMBF) 82DZL00401Bundesministerium für Bildung und Forschung (BMBF) 82DZL004A1Bundesministerium für Bildung und Forschung (BMBF) 82DZL009B1Deutsche Forschungsgemeinschaft (DFG) 431232613 sub-project Z02
6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease, which is usually diagnosed late in advanced stages. Little is known about the subclinical development of IPF. We previously generated a mouse model with conditional

Indexed as

Disease ProgressionNedd4 Ubiquitin Protein LigasesX-Ray MicrotomographyAnimalsDisease Models, AnimalIdiopathic Pulmonary FibrosisLungMiceMice, KnockoutPulmonary FibrosisNedd4l protein, mouseNedd4 protein, mouseNedd4 Ubiquitin Protein Ligasesanimal modelidiopathic pulmonary fibrosisIPFmicro-CTNedd4-2

Identifiers

PMID39437758
PMCPMC11684955

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.