Evidence map›Paper›PMID 39437748›Full record

ReviewCerebrovascular diseases extra2024

Near-Complete Reversal of Large Diffusion-Weighted Imaging Lesion after Thrombectomy: A Case Report and Literature Review.

Huy Quang Dang, Trung Quoc Nguyen, Duc Nguyen Chiem, Tra Vu Son Le, Ryan Anh-Quang Nguyen, Huy Nguyen, Thang Huy Nguyen

Abstract readCase ReportsReview
In one paragraph

Review in Cerebrovascular diseases extra, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huy Quang DangDepartment of Cerebrovascular Disease, 115 People's Hospital, Ho Chi Minh City, Vietnam.
Trung Quoc NguyenDepartment of Cerebrovascular Disease, 115 People's Hospital, Ho Chi Minh City, Vietnam.
Duc Nguyen ChiemDepartment of Cerebrovascular Disease, 115 People's Hospital, Ho Chi Minh City, Vietnam.
Tra Vu Son LeDepartment of Neurointervention, 115 People's Hospital, Ho Chi Minh City, Vietnam.
Ryan Anh-Quang NguyenUniversity of California, Berkeley, California, USA.
Huy NguyenFaculty of Medicine, University of Debrecen, Debrecen, Hungary.
Thang Huy NguyenDepartment of Cerebrovascular Disease, 115 People's Hospital, Ho Chi Minh City, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDiffusion-weighted imaging (DWI) plays a crucial role in acute ischemic stroke (AIS), as it is used to evaluate the ischemic lesions that are irreversibly damaged. The reversibility of DWI ischemic lesions has been noted in patients with AIS who undergo revascularization therapy. In addition, the occurrence of this phenomenon in large ischemic regions remains rare, particularly the near-complete reversal of large DWI lesion cases. CASE PRESENTATION: A 58-year-old male presented with a generalized tonic-clonic seizure. Emergent magnetic resonance imaging (MRI) revealed an extremely large infarction lesion in the right hemisphere with an Alberta Stroke Program Early Computed Tomographic Score (ASPECTS) value of 2 and occlusion of the terminal right internal carotid artery. The patient was immediately transferred to the Digital Subtraction Angiography (DSA) Unit for endovascular treatment with a stent retriever. After a rapid successful reperfusion with expanded treatment in cerebral infarction (eTICI) score of 3, the patient promptly recovered 24 h after the procedure. A brain MRI was repeated after 8 days of admission, and interestingly, the DWI lesion showed significant reversal. The modified Rankin scale (mRS) at discharge was 2 and 1 at 90-day follow-up, respectively.

conclusionsOur case shows that the reversibility of DWI ischemic lesions can occur during the acute stroke phase, even in patients with extremely large regions, if rapid and successful reperfusion is achieved. The clinical implications of this phenomenon indicate that using DWI to evaluate the infarct core should be interpreted with caution.

Indexed as

Diffusion Magnetic Resonance ImagingIschemic StrokePredictive Value of TestsThrombectomyAngiography, Digital SubtractionCarotid StenosisCerebral AngiographyDisability EvaluationHumansMaleMiddle AgedRecovery of FunctionTime FactorsTreatment OutcomeAcute strokeDiffusion-weighted imagingLarge coreReversibleThrombectomy

Identifiers

PMID39437748
PMCPMC11604242

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.