Evidence map›Paper›PMID 39437216›Full record

ArticleRetina (Philadelphia, Pa.)2024

SUPPLEMENTAL DEXTROSE IN THE INFUSION FLUID DURING DIABETIC VITRECTOMY.

Kathleen R Schildroth, Kyle D Peterson, Michael M Altaweel, Roomasa Channa, Jonathan S Chang, Justin L Gottlieb, Michael S Ip, T Michael Nork

Abstract read
In one paragraph

Article in Retina (Philadelphia, Pa.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathleen R SchildrothDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin; and.ORCID 0000-0003-0504-3053
Kyle D PetersonDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin; and.
Michael M AltaweelDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin; and.
Roomasa ChannaDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin; and.
Jonathan S ChangDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin; and.
Justin L GottliebDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin; and.
Michael S IpDoheny Eye Institute, UCLA, Los Angeles, California.
T Michael NorkDepartment of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, Wisconsin; and.

Funding

UW Vision Research Core - Administrative CoreP30EY016665 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI ROBERT W NICKELLS · 2005 to 2026
$12.6M
NEI NIH HHS P30 EY016665
6 · The paper itself

Abstract

purposeHistorically, supplemental dextrose to infusion fluid has been used to reduce the need for intraoperative lensectomies to maintain visualization during diabetic vitrectomy. Valved, small-gauge vitrectomy has reduced surgical time and decreased intraoperative fluid flow. Assessment of supplemental dextrose in modern vitrectomy is presented in this study.

methodsA retrospective cohort study of diabetic patients undergoing vitrectomy was conducted. The dextrose group received supplemental dextrose in the infusion fluid, while the nondextrose group used a standard balanced salt solution (BSS Plus). Group assignment was per surgeons' typical practice patterns. Eyes with tractional retinal detachments were also evaluated as a subgroup.

resultsThree hundred thirty phakic eyes were included. Supplemental dextrose was used in 199 eyes (60.3%). One unplanned lensectomy was performed in this series, in the nondextrose group, not statistically different from the dextrose group, with zero lensectomies (P = 0.4). Cataract survival curves overlapped for all eyes and for the tractional retinal detachment subgroup.

conclusionIn modern vitrectomy, unplanned lensectomy is rare. No difference was observed in the rate of intraoperative lensectomies or overall postoperative cataract course with or without dextrose supplementation to the infusion fluid. Standard solutions appear to be adequate for infusion, even for diabetics.

Indexed as

Diabetic RetinopathyGlucoseVitrectomyAcetatesAgedDrug CombinationsFemaleHumansMaleMiddle AgedMineralsRetinal DetachmentRetrospective StudiesSodium ChlorideVisual AcuityAcetatesBSS solutionDrug CombinationsGlucoseMineralsSodium Chloride

Identifiers

PMID39437216
PMCPMC11884518

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.