Evidence map›Paper›PMID 39437195›Full record

ArticlePacing and clinical electrophysiology : PACE2024

Relationship Between Electrical Parameters and Cardiac Synchrony in Patients Underwent Left Bundle Branch Area Pacing.

Manxin Lin, Shufen Huang, Xinyi Huang, Jincun Guo, Linlin Li, Simei Chen, Guiyang Li, Qiang Li, Dong Chang, Maolong Su and 1 more

Abstract read
In one paragraph

Article in Pacing and clinical electrophysiology : PACE, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Manxin LinDivision of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.ORCID 0000-0002-5406-9711
Shufen HuangDivision of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.
Xinyi HuangDivision of Echocardiography, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.
Jincun GuoDivision of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.ORCID 0000-0002-7120-2203
Linlin LiDivision of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.
Simei ChenDivision of Cardiac Function, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.
Guiyang LiDivision of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.
Qiang LiDivision of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.ORCID 0000-0001-8353-374X
Dong ChangDivision of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.
Maolong SuDivision of Echocardiography, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.
Binni CaiDivision of Cardiology, Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, Fujian, China.

Funding

Key Medical Projects of Xiamen Science and Technology Plan 3502Z20191103Medical Guidance Project of Xiamen 3502Z20244ZD1234
6 · The paper itself

Abstract

purposeThe study aims to assess cardiac synchrony under different left bundle branch area pacing (LBBAP) and evaluate the relationship between different surface or intracardiac electrical parameters and mechanical synchrony.

methodsEighty-two patients with successful LBBAP were recruited. The electrical synchrony, evaluated by paced QRS duration (pQRSD) and Stim-LVAT (stimulus to left ventricular activation time), and mechanical synchrony, evaluated by the standard deviation of the time-to-peak contraction velocity in 12 left ventricular segments (Tsd-12-LV), were compared between groups in patients underwent LBBAP. To investigate the relationship between different electrical parameters with mechanical synchrony under LBBAP, patients were divided into subgroups according to left ventricular activation time (LVAT, < 60, 60-70, and > 70 ms), presence of left bundle branch (LBB) potential (positive, negative), QRS axis (normal, left axis deviation [LAD]), and potential to ventricular interval (PVI, < 20 and > 20 ms). Mechanical synchrony was compared among the subgroups respectively 3 days post LBBAP procedure.

resultsNo statistically significant differences were documented in electrical synchrony, evaluated by pQRSD, and mechanical synchrony, evaluated by Tsd-12-LV among the subgroups divided by the stim-LVAT, LBB potential, PVI duration, or paced QRS axis in the LBBAP group.

conclusionsLBB potential, PVI, or normal paced QRS axis is not the prerequisite for successful LBBAP and optimal cardiac synchrony. Adopting a Stim-LVAT value of less than 75 ms to attain ideal electrical and mechanical synchrony during the LBBAP procedure may be applicable.

trial registrationhttp://www.chictr.org.cn/index.aspx. CLINICALTRIALS: gov identifier: ChiCTR1800021104.

Indexed as

Bundle-Branch BlockCardiac Pacing, ArtificialAgedBundle of HisElectrocardiographyFemaleHumansMaleMiddle AgedTreatment Outcomeelectrical synchronyleft bundle branch area pacingmechanical synchronyphysiological pacing

Identifiers

PMID39437195
PMCPMC11630808

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.