Evidence map›Paper›PMID 39436927›Full record

ArticleInternational journal of methods in psychiatric research2024

A control theoretic approach to evaluate and inform ecological momentary interventions.

Janik Fechtelpeter, Christian Rauschenberg, Hamidreza Jalalabadi, Benjamin Boecking, Therese van Amelsvoort, Ulrich Reininghaus, Daniel Durstewitz, Georgia Koppe

Abstract read
In one paragraph

Article in International journal of methods in psychiatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Trial
  2. Re-engineering the disordered mind: clinical experimentation, dynamical systems, and AI for personalized psychiatry.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. A control theoretic approach to evaluate and inform ecological momentary interventions.International journal of methods in psychiatric research · 2024
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Janik FechtelpeterDepartment of Theoretical Neuroscience, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.ORCID 0000-0003-4424-1685
Christian RauschenbergDepartment of Public Mental Health, CIMH, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
Hamidreza JalalabadiDepartment of Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany.
Benjamin BoeckingCharité, University Hospital Berlin, Berlin, Germany.ORCID 0000-0002-8140-3332
Therese van AmelsvoortDepartment of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands.
Ulrich ReininghausDepartment of Public Mental Health, CIMH, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany.
Daniel DurstewitzDepartment of Theoretical Neuroscience, Central Institute of Mental Health (CIMH), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Georgia KoppeHector Institute for Artificial Intelligence in Psychiatry, CIMH, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

Funding

Deutsche Forschungsgemeinschaft 389624707Deutsche Forschungsgemeinschaft TRR-265 (project A06)European Union's Horizon 2020 Programme (IMMERSE) 945263Hector II FoundationMinisterium für Wissenschaft, Forschung und Kunst Baden-Württemberg 31-7547.223-7/3/2
6 · The paper itself

Abstract

objectivesEcological momentary interventions (EMI) are digital mobile health interventions administered in an individual's daily life to improve mental health by tailoring intervention components to person and context. Experience sampling via ecological momentary assessments (EMA) furthermore provides dynamic contextual information on an individual's mental health state. We propose a personalized data-driven generic framework to select and evaluate EMI based on EMA.

methodsWe analyze EMA/EMI time-series from 10 individuals, published in a previous study. The EMA consist of multivariate psychological Likert scales. The EMI are mental health trainings presented on a smartphone. We model EMA as linear dynamical systems (DS) and EMI as perturbations. Using concepts from network control theory, we propose and evaluate three personalized data-driven intervention delivery strategies. Moreover, we study putative change mechanisms in response to interventions.

resultsWe identify promising intervention delivery strategies that outperform empirical strategies in simulation. We pinpoint interventions with a high positive impact on the network, at low energetic costs. Although mechanisms differ between individuals - demanding personalized solutions - the proposed strategies are generic and applicable to various real-world settings.

conclusionsCombined with knowledge from mental health experts, DS and control algorithms may provide powerful data-driven and personalized intervention delivery and evaluation strategies.

Indexed as

Ecological Momentary AssessmentAdultFemaleHumansMaleSmartphoneTelemedicinecomputational psychiatrycontrol theoryecological momentary assessmentecological momentary interventionmobile health

Identifiers

PMID39436927
PMCPMC11495417

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.