Evidence map›Paper›PMID 39436870›Full record

ArticlePloS one2024

The 123 COVID SCORE: A simple and reliable diagnostic tool to predict in-hospital death in COVID-19 patients on hospital admission.

Małgorzata Ostrowska, Michał Kasprzak, Tomasz Fabiszak, Jacek Gajda, Natalia Jaje-Rykowska, Piotr Michalski, Beata Moczulska, Paulina Nowek, Maciej Piasecki, Marta Pilaczyńska-Cemel and 12 more

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Małgorzata OstrowskaCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.ORCID 0000-0002-3377-2950
Michał KasprzakCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Tomasz FabiszakCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Jacek GajdaGajda-Med District Hospital in Pultusk, Pultusk, Poland.
Natalia Jaje-RykowskaDepartment of Cardiology and Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Piotr MichalskiCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Beata MoczulskaDepartment of Cardiology and Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Paulina NowekDepartment of Cardiology and Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Maciej PiaseckiCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Marta Pilaczyńska-CemelDepartment of Lung Diseases, Neoplasms and Tuberculosis, Faculty of Medicine, Nicolaus Copernicus University, Bydgoszcz, Poland.
Przemysław PodhajskiCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Paulina PrudzicCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Dominika StępniakDepartment of Cardiology and Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Damian ŚwiątkowskiCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Maciej ŻechowiczDepartment of Cardiology and Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Robert GajdaGajda-Med District Hospital in Pultusk, Pultusk, Poland.
Leszek GromadzińskiDepartment of Cardiology and Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, Olsztyn, Poland.
Jacek KryśCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Aldona KubicaCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.
Grzegorz PrzybylskiDepartment of Lung Diseases, Neoplasms and Tuberculosis, Faculty of Medicine, Nicolaus Copernicus University, Bydgoszcz, Poland.
Paweł SzymańskiDepartment of Cardiology, Interventional Cardiology and Electrophysiology with Cardiac Intensive Care Unit, Tertiary Care Hospital, Grudziądz, Poland.
Jacek KubicaCollegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.ORCID 0000-0001-8250-754X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients hospitalized due to Coronavirus disease 2019 (COVID-19) are still burdened with high risk of death. The aim of this study was to create a risk score predicting in-hospital mortality in COVID-19 patients on hospital admission.

methodsIndependent mortality predictors identified in multivariate logistic regression analysis were used to build the 123 COVID SCORE. Diagnostic performance of the score was evaluated using the area under the receiver-operating characteristic curve (AUROC).

resultsData from 673 COVID-19 patients with median age of 70 years were used to build the score. In-hospital death occurred in 124 study participants (18.4%). The final score is composed of 3 variables that were found predictive of mortality in multivariate logistic regression analysis: (1) age, (2) oxygen saturation on hospital admission without oxygen supplementation and (3) percentage of lung involvement in chest computed tomography (CT). Four point ranges have been identified: 0-5, 6-8, 9-11 and 12-17, respectively corresponding to low (1.5%), moderate (13.4%), high (28.4%) and very high (57.3%) risk of in-hospital death. The 123 COVID SCORE accuracy measured with the AUROC was 0.797 (95% CI 0.757-0.838; p<0.0001) in the study population and 0.774 (95% CI 0.728-0.821; p<0.0001) in an external validation cohort consisting of 558 COVID-19 patients.

conclusionsThe 123 COVID SCORE containing merely 3 variables: age, oxygen saturation, and percentage of lung involvement assessed with chest CT is a simple and reliable tool to predict in-hospital death in COVID-19 patients upon hospital admission.

Indexed as

COVID-19HospitalizationHospital MortalityAgedAged, 80 and overFemaleHumansLogistic ModelsMaleMiddle AgedRisk FactorsROC CurveSARS-CoV-2Tomography, X-Ray Computed

Identifiers

PMID39436870
PMCPMC11495612

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