Evidence map›Paper›PMID 39436762›Full record

ArticleThe Journal of antimicrobial chemotherapy2024

Online availability of antibiotics from within the UK: shifting patterns from 2016 to 2023.

Sara Elizabeth Boyd, Nina Zhu, Laura Whitney, Rohan Surya, Alison Helen Holmes, Raheelah Ahmad

Abstract read
In one paragraph

Article in The Journal of antimicrobial chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara Elizabeth BoydDavid Price Evans Global Health and Infectious Disease Research Group, University of Liverpool, Institute of Systems, Molecular & Integrative Biology, William Henry Duncan Building, 6 West Derby Street, Liverpool L7 8TX, UK.ORCID 0000-0001-9935-5263
Nina ZhuNational Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Du Cane Road, London W12 0HS, UK.
Laura WhitneyPharmacy Team, Medical Directorate, NHS England, London Region, Wellington House, London SE1 8UG, UK.
Rohan SuryaHealth Services Research & Management, School of Health and Medical Sciences, City St. George's University of London, London, UK.
Alison Helen HolmesDavid Price Evans Global Health and Infectious Disease Research Group, University of Liverpool, Institute of Systems, Molecular & Integrative Biology, William Henry Duncan Building, 6 West Derby Street, Liverpool L7 8TX, UK.
Raheelah AhmadNational Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Du Cane Road, London W12 0HS, UK.

Funding

Healthcare Associated Infections and Antimicrobial Resistance at Imperial College London 200876Healthcare Associated Infections and Antimicrobial Resistance at Imperial College London in partnership with the UK Health Security AgencyImperial Healthcare PartnersNational Institute for Health ResearchNational Institute for Health Research Health Protection Research UnitNIHR Imperial Patient Safety Translational Research CentreUniversity of CambridgeUniversity of Warwick
6 · The paper itself

Abstract

backgroundWe previously reported a cross-sectional analysis of online pharmacy practices and processes. Since then, the demand for and context of online healthcare has changed. However, the current state of access to and usage of antibiotics obtained online remains poorly understood.

objectivesThis study aimed to: (i) determine the legality of online pharmacies selling antibiotics in the UK; (ii) describe processes for obtaining antibiotics online; (iii) identify antimicrobial stewardship (AMS) and patient safety issues; and (iv) compare data with those obtained in 2016 to understand changes in context, and set priorities for targeted research in antibiotic access and usage.

methodsSearches for 'buy antibiotics online' were conducted using 'Google' and 'Yahoo'. The first 10 websites with unique URL addresses for each were reviewed. Analyses were conducted on evidence of pharmacy registration, prescription requirement, whether choice was 'prescriber-driven' or 'consumer-driven', and whether information was required (allergies, comorbidities, pregnancy) or given (adverse effects) prior to purchase.

resultsTwenty unique URL addresses were analysed. Those evidencing UK location (n = 20; 100%) required a prescription and were appropriately registered. For 11 (55%) online pharmacies, decisions were initially consumer-driven for antibiotic choice, but not for dose or duration; contrasting with 2016 when for most (n = 16; 80%), decisions were consumer-driven for antibiotic choice, dose and quantity.

conclusionsVariation continues to exist in relation to antibiotic practices online. We make several key recommendations for lawmakers and stakeholders. Targeted research, improved public engagement, professional education and new best practice guidelines are urgently needed for online UK antibiotic suppliers.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipPharmaceutical Services, OnlineCross-Sectional StudiesHumansInternetPatient SafetyUnited KingdomAnti-Bacterial Agents

Identifiers

PMID39436762
PMCPMC11641843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.