Evidence map›Paper›PMID 39436525›Full record

ArticleObesity surgery2024

Validity of Continuous Glucose Monitoring for the Diagnosis of Dumping Syndrome After Metabolic Surgery, in Comparison to the Oral Glucose Tolerance Test.

Bethan Price, Monelle Bertrand, Ana Estrade, Pierre Brinas, Géraud Tuyeras, Eric Guillaume, Stéphane Bordes, Emilie Montastier, Hélène Hanaire, Patrick Ritz

Abstract readComparative StudyValidation Study
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In one paragraph

Article in Obesity surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bethan PriceNutrition and Endocrinology Department, CHU de Toulouse, 31059, Toulouse, France.
Monelle BertrandNutrition and Endocrinology Department, CHU de Toulouse, 31059, Toulouse, France.
Ana EstradeNutrition and Endocrinology Department, CHU de Toulouse, 31059, Toulouse, France.
Pierre BrinasDigestive Surgery Department, CHU de Toulouse, 31059, Toulouse, France.
Géraud TuyerasDigestive Surgery Department, CHU de Toulouse, 31059, Toulouse, France.
Eric GuillaumeDiabetes Department, CHU de Toulouse, 31059, Toulouse, France.
Stéphane BordesDiabetes Department, CHU de Toulouse, 31059, Toulouse, France.
Emilie MontastierNutrition and Endocrinology Department, CHU de Toulouse, 31059, Toulouse, France.
Hélène HanaireDiabetes Department, CHU de Toulouse, 31059, Toulouse, France.
Patrick RitzNutrition and Endocrinology Department, CHU de Toulouse, 31059, Toulouse, France. patrick.ritz@wanadoo.fr.ORCID 0000-0001-8105-4008

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDumping syndrome (DS) is a common complication of metabolic surgery, occurring in as many as 40% of bariatric patients. The reference diagnostic test is oral glucose tolerance testing (OGTT) which is often poorly tolerated and may induce false positive results. Continuous glucose monitoring (CGM) is better tolerated and can monitor patients for about 2 weeks in everyday life. This study aimed at testing the diagnostic capacity of CGM in patients with and without DS, as validated by OGTT. MATERIAL AND

methodsThis is a retrospective monocentric study including adults after bariatric surgery, who complained of DS-compatible symptoms and who had OGTT. CGM characteristics were compared in DS-positive (n = 37) and DS-negative patients (n = 14).

resultsNone of the CGM parameters differed between the two groups: mean, variability, time in range, and time above or below range. OGTT induced different hematocrit and pulse rate responses (by DS definition) but no difference in blood glucose values.

conclusionDespite being a better-tolerated test than OGTT, CGM should not be recommended for the diagnosis of DS. It may still be useful for monitoring glucose values in everyday life to help patients modify their diet, when DS is caused by carbohydrates with high glycemic index. The reference diagnostic test for dumping syndrome is poorly tolerated and artificial. CGM is useful in everyday life, and changes in glucose might be a signal of dumping syndrome. However, CGM is not a valid diagnostic test for dumping syndrome.

Indexed as

Blood GlucoseDumping SyndromeGlucose Tolerance TestAdultBariatric SurgeryBlood Glucose Self-MonitoringContinuous Glucose MonitoringFemaleHumansMaleMiddle AgedObesity, MorbidReproducibility of ResultsRetrospective StudiesBlood GlucoseContinuous glucose monitoringDumping syndromObesity surgery

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.