Evidence map›Paper›PMID 39436502›Full record

ReviewHuman cell2024

Application of hydrogel-loaded dental stem cells in the field of tissue regeneration.

Xiaolan Wang, Zejun Zheng, Ying Zhang, Jinmeng Sun, Jian Liu, Yunxia Liu, Gang Ding

Abstract readReview
PubMed Publisher
In one paragraph

Review in Human cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaolan WangSchool of Stomatology, Shandong Second Medical University, Baotong West Street No.7166, Weifang, Shandong Province, China.
Zejun ZhengSchool of Stomatology, Shandong Second Medical University, Baotong West Street No.7166, Weifang, Shandong Province, China.
Ying ZhangSchool of Stomatology, Shandong Second Medical University, Baotong West Street No.7166, Weifang, Shandong Province, China.
Jinmeng SunSchool of Stomatology, Shandong Second Medical University, Baotong West Street No.7166, Weifang, Shandong Province, China.
Jian LiuSchool of Stomatology, Shandong Second Medical University, Baotong West Street No.7166, Weifang, Shandong Province, China.
Yunxia LiuSchool of Stomatology, Shandong Second Medical University, Baotong West Street No.7166, Weifang, Shandong Province, China. yunxialiu@sdsmu.edu.cn.
Gang DingSchool of Stomatology, Shandong Second Medical University, Baotong West Street No.7166, Weifang, Shandong Province, China. dinggang@sdsmu.edu.cn.ORCID http://orcid.org/0000-0003-4597-1639

Funding

National Natural Science Foundation of China 81570945Natural Science Foundation of Shandong Province ZR2021MH051Weifang Kite Capital Scholars Program ydxz2023002
6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are highly favored in clinical trials due to their unique characteristics, which have isolated from various human tissues. Derived from dental tissues, dental stem cells (DSCs) are particularly notable for their applications in tissue repair and regenerative medicine, attributed to their readily available sources, absence of ethical controversies, and minimal immunogenicity. Hydrogel-loaded stem cell therapy is widespread across a variety of injuries and diseases, and has good repair capabilities for both soft and hard tissues. This review comprehensively summarizes the regenerative and differentiation potential of various DSCs encapsulated in hydrogels across different tissues. In addition, the existing problems and future direction are also addressed. The application of hydrogel-DSCs composite has gained substantial progress in the field of tissue regeneration and need in-depth study in the future.

Indexed as

Cell DifferentiationHydrogelsRegenerationRegenerative MedicineHumansMesenchymal Stem CellsStem CellsTissue EngineeringToothHydrogelsDental pulp stem cellsDental stem cellsHydrogelPeriodontal ligament stem cellsTissue regeneration

Identifiers

PMID39436502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.