Evidence map›Paper›PMID 39436463›Full record

ArticleMikrochimica acta2024

Screening and application of aptamers as fluorescent biosensors for selective and sensitive detection of hepatocellular carcinoma and in vivo targeted delivery studies.

Xuyan Liu, Lei He, Zhenxing Fan, Baolin Li, Yunwang Zhao

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuyan LiuHebei Center for Ecological and Environmental Geology Research, Hebei GEO University, Shijiazhuang, 050031, China. xclxy0203@163.com.
Lei HeSchool of Chemistry & Chemical Engineering, Shanghai Jiao Tong University, Shanghai, 200030, China.
Zhenxing FanInner Mongolia International Mongolian Medicine Hospital, Hohhot, 010020, China.
Baolin LiQinhuangdao First Hospital Affiliated to Hebei Medical University, Qinhuangdao, 066000, China.
Yunwang ZhaoSchool of Chemistry & Chemical Engineering, Inner Mongolia University, Hohhot, 010020, China. zhaoyunwang1234@163.com.

Funding

Science Research Project of Hebei Education Department QN2024036the National Natural Science Foundation of China 81560346the Open Project Program of Hebei Center for Ecological and Environmental Geology Research JSYF-202304
6 · The paper itself

Abstract

The incidence of primary hepatocellular carcinoma (HCC) has recently ranked fifth in the world, and the incidence rate is increasing year by year worldwide. Therefore, early diagnosis is the highest priority in the treatment of HCC. In this paper, four anti-HCC aptamers were obtained using magnetic bead SELEX technology. Among them, Apt-1 had the smallest K

Indexed as

Aptamers, NucleotideBiosensing TechniquesCarcinoma, HepatocellularLiver NeoplasmsAnimalsFluorescent DyesHumansLimit of DetectionMiceMolecular Docking SimulationSELEX Aptamer TechniqueAptamers, NucleotideFluorescent DyesCircular dichronismEarly HCC diagnosisFlow cytometryFluorescent biosensorsLuciferase mRNANucleic acid aptamers

Identifiers

PMID39436463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.