Evidence map›Paper›PMID 39436456›Full record

ArticleHead and neck pathology2024

Do not Judge a book by its Cover: A Secretory Carcinoma Arising from a Salivary Gland Heterotopia in Laterocervical lymph-node.

Giulia Querzoli, Carlotta Liberale, Vicenzo Maiolo, Daria Maria Filippini, Elisabetta Nobili, Giambattista Siepe, Annalisa Altimari, Gabriele Molteni, Maria Pia Foschini

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In one paragraph

Article in Head and neck pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giulia Querzoli *Alma Mater Studiorum University of Bologna, Bologna (BO), 40100, Italy. querzoligiulia@gmail.com.
Carlotta Liberale *Unit of Otorhinolaryngology, Head & Neck Department Policlinico G. B. Rossi, University of Verona, Verona, Italy.
Vicenzo MaioloPediatric and Adult CardioThoracic and Vascular, Oncohematologic and Emergency Radiology Unit, Bologna, Italy.
Daria Maria FilippiniMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Elisabetta NobiliMedical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Giambattista SiepeRadiation Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, 40138, Italy.
Annalisa AltimariSolid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Gabriele MolteniDepartment of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Maria Pia FoschiniDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum, Unit of Anatomic Pathology, University of Bologna, Bellaria Hospital, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heterotopia, the occurrence of specific tissues in ectopic sites during embryogenesis, includes the presence of salivary gland tissue in unusual locations. Salivary gland neoplasms arising from heterotopic sites are rare. Secretory Carcinoma (SC) is a rare salivary gland carcinoma characterized by ETV6-NTRK3 fusion gene, very rarely described in salivary gland heterotopia. Here a case of SC originating from salivary gland heterotopia in a neck lymph node is reported, together with a literature review.A 66-year-old male presented with a left neck mass. Imaging and fine needle aspiration cytology indicated a preliminary diagnosis of a benign/low-grade malignancy neoplasm.Following surgery (superficial parotidectomy and mass excision), histological examination revealed SC within an intranodal salivary heterotopia, confirmed by molecular analysis.Heterotopic salivary gland tissue (HSGT) is rare, and its association with neoplasms is even rarer. Tumours arising on HSGT, share histological similarities with those affecting orthotopic salivary glands. This unique case expands the understanding of SC occurrences on HSGT.

Indexed as

ChoristomaLymph NodesSalivary Gland NeoplasmsAgedCarcinomaHumansMaleSalivary GlandsHead and neckHeterotopiaHeterotopic Salivary GlandLymph nodeSecretory Carcinoma

Identifiers

PMID39436456
PMCPMC11496406

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.