ArticleThe journal of physical chemistry letters2024
Extracting the Heterogeneous 3D Structure of Molecular Films Using Higher Dimensional SFG Microscopy.
Article in The journal of physical chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Spiers Memorial Lecture: Vibrations at interfaces.Faraday discussions · 2026Article
- Full Crystallographic Imaging of Hexagonal Boron Nitride Monolayers with Phonon-Enhanced Sum-Frequency Microscopy.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Mixed Domain IR-Hyper-Raman Four Wave Mixing Spectroscopy.The journal of physical chemistry letters · 2026Article
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Authors and funding
4 authors.
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Abstract
Ultrathin molecular films are widespread in both natural and industrial settings, where details of the molecular structure such as density, out-of-plane tilt angles, and in-plane directionality determine their physicochemical properties. Many of these films possess important molecular-to-macroscopic heterogeneity in these structural parameters, which have traditionally been difficult to characterize. Here, we show how extending sum-frequency generation (SFG) microscopy measurements to higher dimensionality by azimuthal-scanning can extract the spatial variation in the three-dimensional molecular structure at an interface. We extend the commonly applied theoretical assumptions used to analyze SFG signals to the study of systems possessing in-plane anisotropy. This theoretical framework is then applied to a phase-separated mixed lipid monolayer to investigate the variation in molecular density and 3D orientation across the chirally packed lipid domains. The results show little variation in out-of-plane structure but a distinct micron-scale region at the domain boundaries with a reduction in both density and in-plane ordering.
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Registered trials
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