Evidence map›Paper›PMID 39435720›Full record

ArticleOral diseases2025

Oral Health-Related Quality of Life in Dutch Adults With Osteogenesis Imperfecta.

Emmanuelle de Kuijper-Timmermans, Lieke Blokland, Maurits de Kuijper, Stanimira Kalaykova, M Carola Zillikens, Natasha M Appelman-Dijkstra, Koert Gooijer, Arjan Harsevoort, Guus J M Janus

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Article in Oral diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emmanuelle de Kuijper-TimmermansVogellanden Center of Rehabilitation Medicine & Special Care in Dentistry, Zwolle, The Netherlands.ORCID https://orcid.org/0009-0005-7336-0327
Lieke BloklandVogellanden Center of Rehabilitation Medicine & Special Care in Dentistry, Zwolle, The Netherlands.ORCID https://orcid.org/0009-0003-7215-6709
Maurits de KuijperDepartment of Restorative Dentistry, Center for Dentistry and Oral Hygiene, University Medical Center Groningen, The University of Groningen, Groningen, The Netherlands.ORCID https://orcid.org/0000-0001-7561-6166
Stanimira KalaykovaDepartment of Dentistry, Radboud University Medical Center, Nijmegen, The Netherlands.ORCID https://orcid.org/0000-0002-5047-4875
M Carola ZillikensErasmus MC Bone Center, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-9186-3423
Natasha M Appelman-DijkstraDivision Endocrinology and Center for Bone Quality, Department of Internal Medicine, Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0001-5035-127X
Koert GooijerExpert Center for Adults With Osteogenesis Imperfecta, Isala Hospital, Zwolle, The Netherlands.ORCID https://orcid.org/0000-0001-7907-8887
Arjan HarsevoortExpert Center for Adults With Osteogenesis Imperfecta, Isala Hospital, Zwolle, The Netherlands.ORCID https://orcid.org/0000-0002-5982-8131
Guus J M JanusExpert Center for Adults With Osteogenesis Imperfecta, Isala Hospital, Zwolle, The Netherlands.ORCID https://orcid.org/0000-0001-8749-2754

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the oral health-related quality of life and its possible risk factors among adults with Osteogenesis Imperfecta using the Oral Health Impact Profile (OHIP)-49 questionnaire. Secondary objectives were to investigate the impact of self-reported Osteogenesis Imperfecta, Dentinogenesis Imperfecta, and age on various dental parameters. MATERIALS AND

methodsA cross-sectional questionnaire was distributed online to 417 Dutch adults with Osteogenesis Imperfecta at three national referral centers. Multivariate linear regression was performed to identify indicators for OHIP-49 Scores. The effect of Osteogenesis Imperfecta, Dentinogenesis Imperfecta, and age on various dental parameters was investigated using logistic regressions (p < 0.05).

resultsOne hundred and fifty-five questionnaires (37.2%) were suitable for analysis. Osteogenesis Imperfecta type III was significantly associated with higher OHIP-49 scores as compared to type I. Symptoms of temporomandibular disorders, missing teeth or dentures also increased the OHIP-49 scores significantly. Osteogenesis Imperfecta type IV and increasing age were associated with missing teeth. There was a 31.94 times (95% CI: 8.56-119.13) higher odds of tooth fracture with self-reported Dentinogenesis Imperfecta.

conclusionsAdults with Osteogenesis Imperfecta type III report a lower oral health-related quality of life compared to Osteogenesis Imperfecta type I adults.

Indexed as

Oral HealthOsteogenesis ImperfectaQuality of LifeAdolescentAdultAgedAge FactorsCross-Sectional StudiesDentinogenesis ImperfectaFemaleHumansMaleMiddle AgedNetherlandsRisk FactorsSelf ReportDentinogenesis ImperfectaOral Health Impact ProfileOral health‐related quality of lifeOsteogenesis Imperfectarare bone conditionrare diseaseself‐reported oral health

Identifiers

PMID39435720
PMCPMC12021325

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.