Evidence map›Paper›PMID 39435699›Full record

ArticlePlant biotechnology journal2025

CuBe: a geminivirus-based copper-regulated expression system suitable for post-harvest activation.

Elena Garcia-Perez, Marta Vazquez-Vilar, Rosa Lozano-Duran, Diego Orzaez

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. The switch-liker's guide to plant synthetic gene circuits.The Plant journal : for cell and molecular biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elena Garcia-PerezInstituto de Biología Molecular y Celular de Plantas, CSIC-UPV, Valencia, Spain.ORCID https://orcid.org/0000-0003-2502-0975
Marta Vazquez-VilarInstituto de Biología Molecular y Celular de Plantas, CSIC-UPV, Valencia, Spain.ORCID https://orcid.org/0000-0001-7175-7818
Rosa Lozano-DuranDepartment of Plant Biochemistry, Centre for Plant Molecular Biology (ZMBP), Eberhard Karls University, Tübingen, Germany.
Diego OrzaezInstituto de Biología Molecular y Celular de Plantas, CSIC-UPV, Valencia, Spain.ORCID https://orcid.org/0000-0003-1662-5403

Funding

Generalitat Valenciana ACIF2020German Federal and State GovernmentsMinisterio de Ciencia e Innovación PID2022-141438OB-I00Ministerio de Ciencia e Innovación TED2021-131171B-I00
6 · The paper itself

Abstract

The growing demand for sustainable platforms for biomolecule manufacturing has fuelled the development of plant-based production systems. Agroinfiltration, the current industry standard, offers several advantages but faces limitations for large-scale production due to high operational costs and batch-to-batch variability. Alternatively, here, we describe the CuBe system, a novel bean yellow dwarf virus (BeYDV)-derived conditional replicative expression platform stably transformed in Nicotiana benthamiana and activated by copper sulphate (CuSO

Indexed as

CopperGeminiviridaeNicotianaCopper SulfateGenetic VectorsPlants, Genetically ModifiedTransgenesCopperCopper Sulfatecopper switchgeminivirusinducible expressionmolecular farmingNicotiana benthamianaplant synthetic biology

Identifiers

PMID39435699
PMCPMC11672746

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.