Evidence map›Paper›PMID 39435501›Full record

ArticleThe Journal of laryngology and otology2025

A matched pair analysis of outcomes after stapler-assisted pharyngeal closure following laryngectomy.

Antony Abraham Paulose, Rajiv Charles Michael, Natarajan Ramalingam, Jeyashanth Riju, Mahasampath Gowri S, Lisa Abraham, Jino Johns L, Manu Mathew, Meera Thomas, Aparna Irodi

Abstract readComparative Study
In one paragraph

Article in The Journal of laryngology and otology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Stapler versus manual closure for pharyngeal repair after total laryngectomy: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Antony Abraham PauloseDepartment of Head and Neck Surgery, Christian Medical College, Vellore, India.
Rajiv Charles MichaelDepartment of Head and Neck Surgery, Christian Medical College, Vellore, India.
Natarajan RamalingamDepartment of Head and Neck Surgery, Christian Medical College, Vellore, India.
Jeyashanth RijuDepartment of Head and Neck Surgery, Christian Medical College, Vellore, India.ORCID https://orcid.org/0000-0003-4750-8111
Mahasampath Gowri SDepartment of Biostatistics, Christian Medical College, Vellore, India.
Lisa AbrahamDepartment of Head and Neck Surgery, Christian Medical College, Vellore, India.
Jino Johns LDepartment of Head and Neck Surgery, Christian Medical College, Vellore, India.
Manu MathewDepartment of Radiation Oncology, Christian Medical College, Vellore, India.
Meera ThomasDepartment of Pathology, Christian Medical College, Vellore, India.
Aparna IrodiDepartment of Radiodiagnosis, Christian Medical College, Vellore, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare perioperative and oncological outcomes between stapler and manual closure in patients undergoing total laryngectomy for advanced endolaryngeal squamous cell carcinoma.

methodsPatients with advanced endolaryngeal tumours operated between July 2017 and July 2023 were retrospectively dichotomised into stapler closure and manual closure cohorts and compared.

resultsSeventy-one patients with a median age of 57 years were included in our study. The median surgical duration was 270 minutes for the manual closure cohort and 245 minutes for the stapler closure cohort. The pharyngo-cutaneous salivary fistula rate was 6 per cent less in the stapler closure cohort. The estimated mean survival was not significantly different 54.5 months (95 per cent, confidence interval 46.3-62.71) in the manual closure cohort versus 28.12 months (95 per cent, confidence interval 23.6-32.63) in the stapler closure cohort (

conclusionStapler closure can be used in endolaryngeal tumours, and it reduces operating time, thus facilitating efficient utilisation of operation time with non-inferior oncological outcomes as compared to traditional manual closure.

Indexed as

Carcinoma, Squamous CellLaryngeal NeoplasmsLaryngectomySurgical StaplersSurgical StaplingAdultAgedAged, 80 and overFemaleHumansMaleMatched-Pair AnalysisMiddle AgedOperative TimePharynxPostoperative Complicationslaryngeal cancerlaryngectomysquamous cell carcinoma of head and necksurgical staplerstreatment outcome

Identifiers

PMID39435501
PMCPMC12303712

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.