Evidence map›Paper›PMID 39435347›Full record

ReviewKidney international reports2024

Biomarkers of Kidney Disease Progression in ADPKD.

Ahmad Ghanem, Abdul Hamid Borghol, Fadi George Munairdjy Debeh, Stefan Paul, Bassel AlKhatib, Peter C Harris, Pranav S Garimella, Christian Hanna, Timothy L Kline, Neera K Dahl and 1 more

Abstract readReview
In one paragraph

Review in Kidney international reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Evolution of Clinical Trial Design in ADPKD.Kidney international reports · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Polycystic Kidney Disease in Children: The Current Status and the Next Horizon.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2025
    Review
  17. Review
  18. Characterizing the ADPKD-Kidney international reports · 2025
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ahmad GhanemDivision of Nephrology and Hypertension, Mayo Clinic, Jacksonville, Florida, USA.
Abdul Hamid BorgholDivision of Nephrology and Hypertension, Mayo Clinic, Jacksonville, Florida, USA.
Fadi George Munairdjy DebehDivision of Nephrology and Hypertension, Mayo Clinic, Jacksonville, Florida, USA.
Stefan PaulDivision of Nephrology and Hypertension, Mayo Clinic, Jacksonville, Florida, USA.
Bassel AlKhatibDivision of Nephrology and Hypertension, Mayo Clinic, Jacksonville, Florida, USA.
Peter C HarrisDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Pranav S GarimellaDivision of Nephrology and Hypertension, University of California San Diego, San Diego, California, USA.
Christian HannaDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Timothy L KlineDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Neera K DahlDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA.
Fouad T ChebibDivision of Nephrology and Hypertension, Mayo Clinic, Jacksonville, Florida, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic kidney disorder and the fourth leading cause of kidney failure (KF) in adults. Characterized by a reduction in glomerular filtration rate (GFR) and increased kidney size, ADPKD exhibits significant variability in progression, highlighting the urgent need for reliable and predictive biomarkers to optimize management and treatment approaches. This review explores the roles of diverse biomarkers-including clinical, genetic, molecular, and imaging biomarkers-in evaluating disease progression and customizing treatments for ADPKD. Clinical biomarkers such as biological sex, the predicting renal outcome in polycystic kidney disease

Indexed as

ADPKDbiomarkerspolycystic kidney diseasepredictive modelprognosistotal kidney volume

Identifiers

PMID39435347
PMCPMC11492289

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.