Evidence map›Paper›PMID 39435189›Full record

ArticleEuropean journal of pediatric surgery reports2024

A Modification of the Newborn Operation for Cloacal Exstrophy: Leaving the Cecal Plate Untouched.

Elizaveta Bokova, Shimon E Jacobs, Laura Tiusaba, Christina P Ho, Briony K Varda, Hans G Pohl, Christina Feng, Victoria A Lane, Caitlin A Smith, Andrea T Badillo and 2 more

Abstract readCase Reports
In one paragraph

Article in European journal of pediatric surgery reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Elizaveta BokovaDivision of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia, United States.ORCID 0000-0003-0712-3508
Shimon E JacobsDepartment of Surgery, Children's National Hospital, Washington, District of Columbia, United States.ORCID 0000-0001-9106-092X
Laura TiusabaDepartment of Surgery, Colorectal and Pelvic Reconstructive Surgery, Children's National Hospital, Washington, District of Columbia, United States.ORCID 0000-0001-8085-8370
Christina P HoDepartment of Urology, Children's National Hospital, Washington, District of Columbia, United States.
Briony K VardaDepartment of Urology, Children's National Hospital, Washington, District of Columbia, United States.
Hans G PohlDepartment of Urology, Children's National Hospital, Washington, District of Columbia, United States.
Christina FengDepartment of Surgery, Colorectal and Pelvic Reconstructive Surgery, Children's National Hospital, Washington, District of Columbia, United States.
Victoria A LaneDepartment of Paediatric Surgery, Great North Children's Hospital, Newcastle Upon Tyne, United Kingdom.
Caitlin A SmithDepartment of Pediatric and Thoracic General Surgery, Seattle Children's Hospital, Seattle, Washington, United States.
Andrea T BadilloDepartment of Colorectal and Pelvic Reconstruction, Children's National Hospital, Washington, District of Columbia, United States.
Richard J WoodDepartment of Pediatric Colorectal and Pelvic Reconstructive Surgery, Nationwide Children's Hospital, Columbus, Ohio, United States.
Marc A LevittDepartment of Surgery, Colorectal and Pelvic Reconstructive Surgery, Children's National Hospital, Washington, District of Columbia, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The conventional approach to managing a newborn with cloacal exstrophy typically includes separating the cecal plate from between the two hemibladders, tubularizing it to be included in the fecal stream, creating an end colostomy, and bringing the two bladder halves together. This study introduces an alternative approach wherein the cecal plate is retained in its original position and designated for future use as an autoaugment of the bladder. Four cases of cloacal exstrophy cases managed between November 2019 and February 2024 are described, with surgical approach and postoperative outcomes reported. Two patients who underwent traditional reconstruction experienced bacterial overgrowth attributed to stasis in the cecal plate, which manifested in increased ostomy output and feeding intolerance. Treatment in these two cases was to remove the cecum from the fecal stream and use it instead for a bladder augment. Learning from these cases, the third and fourth newborn's approach involved retaining the cecum in situ for autoaugmentation of the bladder and performing an ileal to hindgut anastomosis. No postoperative acidosis occurred in these patients. The alternative approach to the newborn management of cloacal exstrophy whereby the cecal plate is left in situ can decrease stasis and postoperative bacterial overgrowth. It allows for an autoaugmentation of the bladder and is technically easier than the traditional rescue of the cecal plate from within the two hemibladders.

Indexed as

bladder augmentationcecumcloacacloacal exstrophyreconstruction

Identifiers

PMID39435189
PMCPMC11493485

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.