Evidence map›Paper›PMID 39435152›Full record

ArticleThe World Allergy Organization journal2024

Pollen exposures in pregnancy and early life are associated with childhood asthma incidence.

Rajesh Melaram, James Adefisoye, Donald E Warden, Stephen Potter, Hasan Arshad, Hongmei Zhang

Erratum issuedAbstract read
In one paragraph

Article in The World Allergy Organization journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Rajesh MelaramCollege of Nursing and Health Sciences, Texas A&M University - Corpus Christi, Corpus Christi, TX, USA.
James AdefisoyeDivision of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.
Donald E WardenDivision of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.
Stephen PotterIsle of Wight NHS Trust, Newport, Isle of Wight, UK.
Hasan ArshadDavid Hide Asthma and Allergy Research Centre, St. Mary's Hospital, Newport, Isle of Wight, UK.
Hongmei ZhangDivision of Epidemiology, Biostatistics and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA.

Funding

Does epigenetic methylation explain the gender-switch in adolescent asthma?R01AI121226 · NIAID · UNIVERSITY OF MEMPHIS · PI HOLLOWAY, JOHN W, ZHANG, HONGMEI · 2016 to 2020
$3.2M
NIAID NIH HHS R01 AI121226
6 · The paper itself

Abstract

Background: Pollen exposure is an environmental risk factor for asthma symptoms and allergic reactions in children. The extent to which pollen exposure in pregnancy and the first year of life influences the development of childhood asthma and rhinitis is not fully understood. Objective: We aimed to investigate early life exposures to pollen with childhood asthma and rhinitis at age 6 in a longitudinal birth cohort of the United Kingdom. Methods: In this retrospective cohort study, via logistic regressions, we analyzed the associations between pollen exposures in pregnancy and the first year of life with childhood asthma and rhinitis. Results: Higher pollen exposure accumulated during pregnancy and during the first year of life both associated with an increased odds of asthma at age 6 (OR = 1.14, 95% CI 1.03-1.26, p = 0.01; OR = 1.15, 95% CI 1.03-1.29, p = 0.02, respectively). We did not observe statistically significant associations between early life pollen exposures and the odds of rhinitis at the same age. Conclusion: High pollen exposure during early life (prenatal and postnatal) associated with an increased risk of asthma incidence at age 6. Further studies are desired to validate these findings and to elucidate the mechanisms of early life exposures to pollen on asthma etiology.

Indexed as

Childhood asthmaEarly lifePollenPregnancyRhinitis

Identifiers

PMID39435152
PMCPMC11491945

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.