ArticleHealth science reports2024
Examining the link between gut microbiota and periodontitis in East Asians using Mendelian randomization.
Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Causal effects of gut microbiota on periodontitis risk: a meta-analysis of Mendelian randomization studies.BMC oral health · 2025Pooled it
- Examining the link between gut microbiota and periodontitis in East Asians using Mendelian randomization.Health science reports · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study explores the possible connection between periodontitis and gut microbiota in East Asians, a relationship that has been largely unexplored until now. Methods: Using publicly available genome-wide association study (GWAS) data, we performed Mendelian randomization (MR). We analyzed GWAS summary statistics to assess if gut microbiota could causally influence periodontitis risk. We applied methods such as MR-Egger, weighted median, inverse variance weighting, and simple MR, and conducted sensitivity analyses to confirm our findings. Results: Utilizing the Inverse-Variance Weighted approach, we identified potential causal relationships between 17 host-genetically influenced gut microbiota characteristics and periodontitis, including Conclusion: This study reveals a causal relationship between specific microorganisms and periodontitis in the Asian population, shedding light on the influence of gut microbiota on periodontitis.
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Registered trials
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