ArticleRSC advances2024
Optical detection of uric acid based on a citric acid functionalized copper-doped biochar nanozyme.
Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Uricase-free and cost-effective colorimetric assay for uric acid based on CoBTC metal-organic frameworks.Scientific reports · 2025Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Uric acid is the end product of purine metabolism and is a key biomarker for various diseases. Under normal conditions, there is a balance between its production and excretion. Its higher concentration can cause inflammation and severe pain, which makes it necessary to monitor its level for the diagnosis, management, and treatment of various pathological conditions. The current work reports on the synthesis of a copper-doped biochar (Cu@BC) nanocomposite and its functionalization with citric acid. The synthesis of the mimic enzyme was confirmed through various spectroscopic techniques. The nanozyme catalyzes hydrogen peroxide to oxidize tetramethylbenzidine (TMB) with an optical change from colorless to blue-green. This optical transformation was confirmed through a UV-vis spectrophotometer, which gave an expected
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