Evidence map›Paper›PMID 39434993›Full record

ArticleRSC advances2024

Novel pyrimidine linked acyl thiourea derivatives as potent α-amylase and proteinase K inhibitors: design, synthesis, molecular docking and ADME studies.

Hina Zaman, Aamer Saeed, Hammad Ismail, Sadaf Anwaar, Muhammad Latif, Muhammad Zaffar Hashmi, Hesham R El-Seedi

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Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Synthesis, structure and computational study ofActa crystallographica. Section E, Crystallographic communications · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Hina ZamanDepartment of Chemistry, Quaid-I-Azam University Islamabad 45320 Pakistan asaeed@qau.edu.pk +92-51-9064-224 +92-51-9064-2128.
Aamer SaeedDepartment of Chemistry, Quaid-I-Azam University Islamabad 45320 Pakistan asaeed@qau.edu.pk +92-51-9064-224 +92-51-9064-2128.ORCID https://orcid.org/0009-0003-9432-1445
Hammad IsmailDepartment of Biochemistry and Biotechnology, University of Gujrat Gujrat 50700 Pakistan hammad.ismail@uog.edu.pk.
Sadaf AnwaarDepartment of Biological Sciences, International Islamic University Islamabad 45500 Pakistan sadaf.anwaar@iiu.edu.pk.
Muhammad LatifCentre for Genetics and Inherited Diseases (CGID), Taibah University Al-Madinah Al-Munawwarah Kingdom of Saudi Arabia latifmayo@yahoo.com.
Muhammad Zaffar HashmiDepartment of Environmental Health and Management, Health Services Academy Islamabad Pakistan muhammadzaffar.hashmi@fulbrightmail.org.
Hesham R El-SeediDepartment of Chemistry, Faculty of Science, Islamic University of Madinah Madinah 42351 Saudi Arabia elseedi_99@yahoo.com.ORCID https://orcid.org/0000-0002-2519-6690

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To discover promising therapeutic agents, novel diaryl pyrimidine linked acyl thiourea derivatives (6a-j) were designed and synthesized

Identifiers

PMID39434993
PMCPMC11492202

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.