Evidence map›Paper›PMID 39434983›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2024

Frequency and Sex-Specific Associations of Metabolic Syndrome in Rwandans Seeking Outpatient Care: A Cross Sectional, Single Centre Study.

James Gafirita, Cuthbert Musarurwa, Evariste Ntaganda, Marguerite Uwimana, Aime Dieudonne Hirwa, Mediatrice Mukahigiro, Laetitia Twizelimana, Marie Louise Nshimirimana, Stephen Rulisa, Charlotte Bavuma and 2 more

Abstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

James Gafirita *Department of Biomedical Laboratory Sciences College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Cuthbert Musarurwa *Department of Biomedical Laboratory Sciences College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.ORCID 0000-0001-8248-427X
Evariste Ntaganda *Division of Non-Communicable Diseases, Rwanda Biomedical Center (RBC), Ministry of Health, Kigali, Rwanda.
Marguerite Uwimana *Department of NCD, Ruhengeri Provincial Hospital, Musanze, Northern Province, Rwanda.
Aime Dieudonne Hirwa *Department of Surgery, Ruhengeri Provincial Hospital, Musanze, Northern Province, Rwanda.
Mediatrice Mukahigiro *Department of Laboratory Diagnosis, Ruhengeri Provincial Hospital, Musanze, Northern Province, Rwanda.
Laetitia Twizelimana *Department of Internal Medicine, Ruhengeri Provincial Hospital, Musanze, Northern Province, Rwanda.
Marie Louise Nshimirimana *Department of Internal Medicine, Ruhengeri Provincial Hospital, Musanze, Northern Province, Rwanda.
Stephen RulisaDepartment of Obstetrics and Gynecology, Kigali University Teaching Hospital, Kigali, Rwanda.ORCID 0000-0002-5357-7626
Charlotte Bavuma *Department of Obstetrics and Gynecology School of Medicine and Pharmacy, College of Medicine and Health Science, University of Rwanda, Kigali, Rwanda.
Emile IvanDepartment of Drugs Assessment and Registration, Division of Human Medicine and Device Registration, Rwanda Food and Drugs Authority, Kigali, Rwanda.
David K Tumusiime *Department of Physiotherapy School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prevalence of cardiometabolic diseases is escalating in sub-Saharan Africa (SSA) alongside the prevailing high burden of communicable diseases. Although many countries in SSA, including Rwanda, have existing data on the prevalence of individual components of the MetS, many SSA countries have insufficient data to guide policy makers on the magnitude of MetS. This study sought to determine the magnitude of MetS and its associated risk factors by sex at a referral teaching hospital in Rwanda. Methods: A cross-sectional, study was conducted among adults aged 35 to 65 years presenting at Ruhengeri Referral Teaching Hospital, Rwanda. We collected socio-clinicodemographic data using the World Health Organization (WHO) STEPwise tool for non-communicable diseases. We used the National Cholesterol Education Program Adult Treatment Panel III criteria for MetS. Results: Overall, 99 (23.5%) males and 322 (76.5%) female participants with mean ± SD age 47.5 ± 8.2 years were enrolled. The overall frequency of MetS was 51.9% (95% CI: 47.0-56.8) and was significantly higher (p < 0.001) in females 193 (59.4%) compared to males 26 (26.3%). Significant differences by sex were also noted in the proportions of visceral obesity; 70.4% vs 7.1% (p < 0.001), hypoalphalipoproteinaemia 36.1% vs 69.7% (p < 0.0001), type 2 diabetes mellitus; 18.4% vs 31.6% (p = 0.020) and body mass index 25.9 ± 15.6 vs 28.2 ± 6.4 (p = 0.032). On multivariate logistic regression, older age (odds ratio (OR) 1.05; 95% confidence interval ((CI) 1.01-1.10)), higher body weight (OR 1.06; 95% CI 1.04-1.08) and higher total cholesterol (1.25; 95% CI 1.05 -1.74) were significantly associated with MetS in females; whereas only higher body weight (OR1.10; 95% CI 1.04-1.18) was significantly associated with MetS in males. Conclusion: A high frequency of MetS was observed in the present study, which was higher among females. Our findings emphasize the need for tailored prevention and intervention strategies to mitigate the long-term impact of MetS.

Indexed as

frequencymetabolic syndromenon-communicable diseasesRwanda

Identifiers

PMID39434983
PMCPMC11492906

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.