Evidence map›Paper›PMID 39434965›Full record

ArticleInfection prevention in practice2024

Antibiotic prophylaxis practice in gastrointestinal surgery in five hospitals in southern Benin.

Dessièdé Ariane Fiogbe, Angèle Modupè Dohou, Carine Laurence Yehouenou, Séverine Henrard, Françoise Van Bambeke, Francis Moïse Djidénou Dossou, Olivia Dalleur

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Article in Infection prevention in practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Dessièdé Ariane FiogbeClinical Pharmacy and Pharmacoepidemiology research group (CLIP), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.
Angèle Modupè DohouClinical Pharmacy and Pharmacoepidemiology research group (CLIP), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.
Carine Laurence YehouenouClinical Pharmacy and Pharmacoepidemiology research group (CLIP), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.
Séverine HenrardClinical Pharmacy and Pharmacoepidemiology research group (CLIP), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.
Françoise Van BambekePharmacologie Cellulaire et Moléculaire, Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.
Francis Moïse Djidénou DossouFaculté des Sciences de la Santé (FSS), Université d'Abomey Calavi (UAC), Cotonou, Benin.
Olivia DalleurClinical Pharmacy and Pharmacoepidemiology research group (CLIP), Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Benin's healthcare system is characterized by a lack of local guidelines for surgical antibiotic prophylaxis (SAP), which is essential to prevent surgical site infection. Aim: To audit compliance for SAP practices in gastrointestinal surgery. Methods: Data were prospectively collected from gastrointestinal surgery departments in five hospitals. Over a four month period, SAP was assessed using five conventional criteria (indication, choice of antibiotic, dosage, timing, and duration of administration) among patients admitted for Altemeier class 1 or 2 procedures. Three guidelines were used as reference: World Health Organization (WHO), American Society of Health-System Pharmacists (ASHP)and French Society of Anaesthesia and Intensive Care Medicine (SFAR). Findings: Of 68 surgical interventions, overall compliance with WHO, ASHP, and SFAR was observed in zero (0.0%), one case (1.5%) and two cases (2.9%), respectively. Compliance with indication varied according to the guidelines: 65 (95.6%) were compliant with WHO and ASHP and 47 cases (69.11%) with SFAR. Among compliant cases, the antibiotics administered were rarely selected according to guidelines: WHO, 2 (2.9%) and ASHP, 2 (2.9%), and SFAR, 3 (4.4%). Drug dosage compliance varied from 20 (29.4%) (SFAR) to 49 (72.0%) (ASHP). Timings were respected in 47 (69.1%; WHO), 45 (66.2%; ASHP) and 9 cases (13.2%; SFAR). The number of cases compliant with antibiotic prophylaxis duration were 13 (19.1%; WHO), 17 (25.0%; ASHP) and 16 (23.5%; SFAR). Conclusion: The SAP compliance rate in gastrointestinal surgery based on the five conventional criteria was very low. SAP guidelines must be implemented appropriately for local bacteriological epidemiology.

Indexed as

Antibiotic prophylaxisAuditComplianceGastrointestinal surgery

Identifiers

PMID39434965
PMCPMC11491886

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.