Evidence map›Paper›PMID 39434837›Full record

ArticleFrontiers in neurology2024

Gait analysis in the early stage of Parkinson's disease with a machine learning approach.

Wenchao Yin, Wencheng Zhu, Hong Gao, Xiaohui Niu, Chenxin Shen, Xiangmin Fan, Cui Wang

Abstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenchao YinDepartment of Neurology, Central Hospital of Dalian University of Technology, Dalian, China.
Wencheng ZhuBeijing CAS-Ruiyi Information Technology Co., Ltd., Beijing, China.
Hong GaoSchool of Science, Dalian Maritime University, Dalian, China.
Xiaohui NiuDepartment of Neurology, Central Hospital of Dalian University of Technology, Dalian, China.
Chenxin ShenDepartment of Neurology, Central Hospital of Dalian University of Technology, Dalian, China.
Xiangmin FanInstitute of Software, Chinese Academy of Sciences, Beijing, China.
Cui WangDepartment of Neurology, Central Hospital of Dalian University of Technology, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gait disorder is a prominent motor symptom in Parkinson's disease (PD), objective and quantitative assessment of gait is essential for diagnosing and treating PD, particularly in its early stage. Methods: This study utilized a non-contact gait assessment system to investigate gait characteristics between individuals with PD and healthy controls, with a focus on early-stage PD. Additionally, we trained two machine learning models to differentiate early-stage PD patients from controls and to predict MDS-UPDRS III score. Results: Early-stage PD patients demonstrated reduced stride length, decreased gait speed, slower stride and swing speeds, extended turning time, and reduced cadence compared to controls. Our model, after an integrated analysis of gait parameters, accurately identified early-stage PD patients. Moreover, the model indicated that gait parameters could predict the MDS-UPDRS III score using a machine learning regression approach. Conclusion: The non-contact gait assessment system facilitates the objective and quantitative evaluation of gait disorder in PD patients, effectively distinguishing those in the early stage from healthy individuals. The system holds significant potential for the early detection of PD. It also harnesses gait parameters for a reasoned prediction of the MDS-UPDRS III score, thereby quantifying disease severity. Overall, gait assessment is a valuable method for the early identification and ongoing monitoring of PD.

Indexed as

early-stage diagnosisgait analysismachine learningMDS-UPDRS III scorenon-contact assessmentParkinson’s disease

Identifiers

PMID39434837
PMCPMC11491890

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.