Evidence map›Paper›PMID 39434793›Full record

SynthesisPeerJ2024

The relationship between allergic rhinitis and attention deficit hyperactivity disorder: a systematic review and meta-analysis.

Qian Wang, Ruikun Wang, Mengyao Li, Jieqiong Liang, Xiaojun Zhan, Yingxia Lu, Guimin Huang, Qinglong Gu

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qian Wang *Department of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, China.
Ruikun Wang *Capital Institute of Pediatrics-Peking University Teaching Hospital, Beijing, China.
Mengyao LiDepartment of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, China.
Jieqiong LiangDepartment of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, China.
Xiaojun ZhanDepartment of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, China.
Yingxia LuDepartment of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, China.
Guimin HuangChild Health Big Data Research Center, Capital Institute of Pediatrics, Beijing, China.ORCID 0000-0003-3477-0612
Qinglong GuDepartment of Otolaryngology-Head and Neck Surgery, Capital Institute of Pediatrics, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Numerous investigations have examined the potential link between allergic rhinitis (AR) and attention deficit hyperactivity disorder (ADHD). However, some studies show no association between the two diseases. The connection between these two conditions remains inconclusive. This study aimed to conduct a meta-analysis exploring the correlation between AR and ADHD. Methods: We conducted systematic searches of the MEDLINE, EMBASE, Cochrane Library, ERIC, PubMed, Web of Science, and CINAHL databases, up to the year 2023. Subsequently, we conducted a meta-analysis using R 4.2.2, where we computed the pooled odds ratio with a 95% confidence interval to assess the relationship between AR and ADHD within studies exhibiting similar characteristics. Statistical heterogeneity was evaluated by computing the value using the Cochrane Intervention Manual's guidelines. Additionally, subgroup analyses were conducted by stratifying the study population according to gender, age, Results: In this systematic review, we incorporated 12 eligible studies, collectively encompassing a sample size of 530,360 participants. Within the included studies, heterogeneity was observed, and the utilization of a random-effects model demonstrated a noteworthy correlation between children with ADHD and the presence of AR. Similarly, children with AR exhibited a significant correlation with the occurrence of ADHD. We also found some relationships in subgroup analyses. Conclusion: A substantial correlation is evident between AR and ADHD in children and adolescents. AR may potentially contribute as a risk factor for the onset of ADHD, and conversely, ADHD may heighten the likelihood of developing AR.

Indexed as

Attention Deficit Disorder with HyperactivityRhinitis, AllergicAdolescentChildFemaleHumansMaleAdolescentsAllergic rhinitis (AR)Attention-deficit/hyperactivity disorder (ADHD)ChildrenMeta-analysisSystematic review

Identifiers

PMID39434793
PMCPMC11493030

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.