Evidence map›Paper›PMID 39434361›Full record

ArticleKorean circulation journal2025

The Korean Organ Transplant Registry (KOTRY): Third Official Adult Heart Transplant Report.

Hyo-In Choi, Sang Eun Lee, Junho Hyun, Darae Kim, Dong-Ju Choi, Eun-Seok Jeon, Hae-Young Lee, Hyun-Jai Cho, Hyungseop Kim, In-Cheol Kim and 9 more

Abstract read
In one paragraph

Article in Korean circulation journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Hyo-In ChoiDivision of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6216-0873
Sang Eun LeeDivision of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. sangeunlee.md@gmail.com.ORCID https://orcid.org/0000-0002-7290-2463
Junho HyunDivision of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4211-3081
Darae KimDepartment of Internal Medicine, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3284-0904
Dong-Ju ChoiDivision of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0003-0146-2189
Eun-Seok JeonDepartment of Internal Medicine, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9946-5611
Hae-Young LeeDivision of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-9521-4102
Hyun-Jai ChoDivision of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-2779-4037
Hyungseop KimDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0001-7056-4221
In-Cheol KimDivision of Cardiology, Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.ORCID https://orcid.org/0000-0002-5751-2328
Jaewon OhDepartment of Cardiology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4585-1488
Minjae YoonDivision of Cardiology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0003-4209-655X
Jin Joo ParkDivision of Cardiology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.ORCID https://orcid.org/0000-0001-9611-1490
Jin-Oh ChoiDepartment of Internal Medicine, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2441-2267
Min Ho JuDepartment of Thoracic and Cardiovascular Surgery and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Korea.ORCID https://orcid.org/0000-0001-7839-8598
Seok-Min KangDepartment of Cardiology, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9856-9227
Soo Yong LeeDivision of Cardiology, Department of Internal Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.ORCID https://orcid.org/0000-0003-2616-1294
Sung-Ho JungDepartment of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3699-0312
Jae-Joong KimDivision of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2714-2282

Funding

Korea National Institute of Health 2014-ER6301-00Korea National Institute of Health 2014-ER6301-01Korea National Institute of Health 2014-ER6301-02Korea National Institute of Health 2017-ER6301-00Korea National Institute of Health 2017-ER6301-01Korea National Institute of Health 2017-ER6301-02Korea National Institute of Health 2020-ER7201-00Korea National Institute of Health 2020-ER7201-01Korea National Institute of Health 2020-ER7201-02Korea National Institute of Health 2023-ER0805-00Korea National Institute of Health 2023-ER0805-01
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe Korean Organ Transplant Registry (KOTRY) provided data for this third official report on adult heart transplantation (HT), including information from 709 recipients.

methodsData from HTs performed at seven major centers in Korea between March 2014 and December 2020 were analyzed, focusing on immunosuppression, acute rejection, cardiac allograft vasculopathy (CAV), post-transplant survival, and mechanical circulatory support (MCS) usage.

resultsThe median ages of the recipients and donors were 56.0 and 43.0 years, respectively. Cardiomyopathy and ischemic heart disease were the most common preceding conditions for HT. A significant portion of patients underwent HT at waiting list status 1 and 0. In the multivariate analysis, a predicted heart mass mismatch was associated with a higher risk of 1-year mortality. Patients over 70 years old had a significantly increased risk of 6-year mortality. The risk of CAV was higher for male donors and donors older than 45 years. Acute rejection was more likely in patients with panel reactive antibody levels above 80%, while statin use was associated with a reduced risk. The employment of left ventricular assist device as a bridge to transplantation increased from 2.17% to 22.4%. Pre-transplant extra-corporeal membrane oxygenation was associated with worse post-transplant survival.

conclusionsIn this third KOTRY report, we analyzed changes in the characteristics of adult HT recipients and donors and their impact on post-transplant outcomes. The most notable discovery was the increased use of MCS before HT and their impact on post-transplant outcomes.

Indexed as

Heart failureHeart transplantationRegistries

Identifiers

PMID39434361
PMCPMC11875971

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.