ArticleBMC public health2024
Associations between the geriatric nutritional risk index and the risk of and mortality associated with chronic kidney disease in older individuals.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed.
- Comparative Analysis of Surrogate Insulin Resistance Indexes in Cardiometabolic Multimorbidity: A Cross-Sectional Study.Reviews in cardiovascular medicine · 2026Article
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- Geriatric nutritional risk index and mortality risk in elderly patients with rheumatoid arthritis: evidence from NHANES (1999-2018).Clinical rheumatology · 2026Article
- [The value of the nutritional assessment index or score in prognostic evaluation for patients with liver cancer].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Review
- Article
- Association between Geriatric Nutritional Risk Index (GNRI) and all-cause mortality in centenarians, with a focus on nonlinear and threshold effects: a multi-method observational study.Frontiers in nutrition · 2026Article
- The Geriatric Nutritional Risk Index and its association with all-cause mortality in cancer patients with sepsis: a dual-center retrospective cohort study.Frontiers in nutrition · 2026Article
- Association of Prognostic Nutritional Index With Mortality in High-Risk OSA Individuals and with Disease Severity in Clinical OSA Patients.Nature and science of sleep · 2026Article
- Sex modifies the association between malnutrition and chronic kidney disease in community-dwelling older adults in the United States.BMC geriatrics · 2025Article
- Nutrition across the Entire Lifespan in CKD: From Childhood to Senescence.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Association between the geriatric nutritional risk index with the risk of frailty and mortality in the elderly population.Scientific reports · 2025Article
- Predictive value of Geriatric Nutritional Risk Index for overall survival in maintenance hemodialysis patients.Frontiers in nutrition · 2025Article
- Nutritional status affects inflammatory responses and exacerbates the severity of pulmonary tuberculosis.Frontiers in cellular and infection microbiology · 2025Article
- Geriatric Nutritional Risk Index and mortality in individuals with prediabetes and diabetes: a longitudinal cohort study.Frontiers in nutrition · 2025Article
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Abstract
backgroundMalnutrition is a complication of chronic kidney disease (CKD). Whether malnutrition, assessed via the geriatric nutritional risk index (GNRI), is associated with the incidence and risk of CKD in older individuals remains unclear.
methodsData from the National Health and Nutrition Examination Survey and the UK Biobank database were used. Older participants over 60 years old with available data for GNRI assessment and CKD diagnosis were enrolled. Logistic regression models and Cox regression models were used to assess associations between the geriatric nutritional risk index and the risk of and mortality associated with CKD.
resultsThis study enrolled 13,162 participants from the NHANES and 66,326 participants from the UK Biobank. We identified 6,135 and 16,662 CKD patients in the NHANES and UK Biobank, respectively, with the majority being male (74% in the NHANES and 52% in the UK Biobank). The average age of CKD patients was 72.3 (SD 7.2) years in the NHANES and 64.9 (SD 2.9) years in the UK Biobank. The median follow-up times of older CKD patients were 81 months and 162 months in the NHANES and UK Biobank, respectively. According to the cross-sectional analysis, individuals with a lower GNRI had an increased likelihood of having CKD, with odds ratios of 1.38 (95% CI: 1.05-1.80, P = 0.020) in the NHANES and 2.35 (95% CI: 1.89-2.92, P < 0.001) in the UK Biobank. According to our analysis of the risk of incident CKD in the UK Biobank, a lower GNRI was associated with a greater incidence of CKD (HR: 1.11, 95% CI: 1.04-1.18; P = 0.002). According to the analysis of the risk of mortality, a lower GNRI was associated with an increased risk of death among older CKD patients (NHANES: HR: 1.69, 95% CI: 1.13-2.53, P = 0.011; UK Biobank: HR: 2.28, 95% CI: 1.94-2.69, P < 0.001).
conclusionMalnutrition assessed by the GNRI was significantly and independently associated with the incidence of CKD. Moreover, CKD patients with malnutrition also have a high risk of mortality.
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