Evidence map›Paper›PMID 39434035›Full record

ArticleBMC public health2024

Prolonged exposure to air pollution and risk of acute kidney injury and related mortality: a prospective cohort study based on hospitalized AKI cases and general population controls from the UK Biobank.

Minghui Liu, Meng Gao, Dan Hu, Jiao Hu, Jing Wu, Zhiyong Chen, Jinbo Chen

Abstract read
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Effects of microplastics and nanoplastics on the kidneys.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Review
  4. Atmospheric stressors and kidney diseases.Nature reviews. Nephrology · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Minghui LiuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Meng GaoDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Dan HuDepartment of Urology, Liuyang Jili Hospital, Liuyang, China.
Jiao HuDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China.
Jing WuOffice of Public Health and Medical Emergency Management, Xiangya Hospital, Central South University, Changsha, China. wujing7347@163.com.
Zhiyong ChenDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China. jeffastone@126.com.
Jinbo ChenDepartment of Urology, Xiangya Hospital, Central South University, Changsha, 410008, China. chenjinbo@csu.edu.cn.

Funding

Huxiang Youth Talent Support Program 2021RC3027National Natural Science Foundation of China 82373337Natural Science Foundation of Hunan Province 2023JJ30870
6 · The paper itself

Abstract

backgroundPrevious investigations identified a connection between air pollution and kidney diseases. Nevertheless, there is a lack of comprehensive evidence on the long-term risks posed by air pollution with respect to acute kidney injury (AKI) and AKI-related death.

methodsThis prospective cohort analysis included 414,885 UK Biobank (UKB) participants who did not exhibit AKI at the study's outset. AKI was defined based on ICD-10 codes recorded for hospitalized patients. Cox proportional hazards models were used to assess the association between prolonged exposure to air pollutants (particulate matter with diameters of 2.5 micrometers or less (PM

resultsOver an average follow-up duration of 11.7 years, 14,983 cases of AKI and 326 cases of AKI-related death were diagnosed. Quartile analysis showed individuals exposed to higher levels of these air pollutants had a significantly higher risk of developing AKI and AKI-related death compared to those in the lowest quartile (all P < 0.05). The RCS curves depicting the relationship between PM

conclusionOur study reveals a direct association between prolonged air pollution exposure and elevated risks of both AKI and AKI-related death. These findings offer scientific validation for the adoption of environmental and public health measures directed towards the reduction of air pollution. Such initiatives could potentially ease the impact associated with AKI and AKI-related death.

Indexed as

Acute Kidney InjuryAir PollutionEnvironmental ExposureParticulate MatterAdultAgedAir PollutantsBiological Specimen BanksCase-Control StudiesFemaleHospitalizationHumansMaleMiddle AgedProportional Hazards ModelsProspective StudiesAir PollutantsParticulate MatterAir pollutionAKIAKI-related deathNO2PM2.5

Identifiers

PMID39434035
PMCPMC11495112

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.