Evidence map›Paper›PMID 39433900›Full record

ArticleThe EMBO journal2024

BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells.

Yehua Li, Xiaodan Wang, Meimei Huang, Xu Wang, Chunlin Li, Siqi Li, Yuhui Tang, Shicheng Yu, Yalong Wang, Wanglu Song and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The EMBO journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yehua Li *The State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.ORCID http://orcid.org/0000-0002-6886-7087
Xiaodan Wang *The State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.ORCID http://orcid.org/0009-0007-4421-9708
Meimei Huang *The State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.ORCID http://orcid.org/0000-0002-1359-443X
Xu WangGuangzhou National Laboratory, Guangzhou, 510700, China.
Chunlin LiThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Siqi LiGuangzhou National Laboratory, Guangzhou, 510700, China.
Yuhui TangThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Shicheng YuGuangzhou National Laboratory, Guangzhou, 510700, China.
Yalong WangGuangzhou National Laboratory, Guangzhou, 510700, China.ORCID http://orcid.org/0000-0002-5477-4488
Wanglu SongThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.ORCID http://orcid.org/0000-0003-2785-0534
Wei WuMOE Key Laboratory of Protein Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China.
Yuan LiuThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China. liu-yuan@mail.tsinghua.edu.cn.ORCID http://orcid.org/0009-0002-2877-9354
Ye-Guang ChenThe State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, 100084, China. ygchen@tsinghua.edu.cn.ORCID http://orcid.org/0000-0002-6701-0065

Funding

| Beijing Science and Technology Planning Project (Beijing Science and Technology Plan Project) Z231100007223006MOST | National Key Research and Development Program of China (NKPs) 2023YFA1800603MOST | National Natural Science Foundation of China (NSFC) 31988101MOST | National Natural Science Foundation of China (NSFC) 92354306| Natural Science Foundation of Jiangxi Province (Jiangxi Natural Science Foundation) 20224ACB209001Shenzhen Medical Research Fund B2302022
6 · The paper itself

Abstract

Lgr5

Indexed as

Bone Morphogenetic ProteinsIntestinal MucosaMi-2 Nucleosome Remodeling and Deacetylase ComplexRepressor ProteinsStem CellsWnt Signaling PathwayAnimalsbeta CateninCell ProliferationHumansMiceMice, Inbred C57BLReceptors, G-Protein-CoupledTumor Suppressor ProteinsBCL11B protein, humanbeta CateninBone Morphogenetic ProteinsLgr5 protein, mouseMi-2 Nucleosome Remodeling and Deacetylase ComplexReceptors, G-Protein-CoupledRepressor ProteinsTumor Suppressor ProteinsBcl11bBMP SignalingColorectal CancerIntestinal Stem CellsWnt Signaling

Identifiers

PMID39433900
PMCPMC11612440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.