Evidence map›Paper›PMID 39433834›Full record

SynthesisScientific reports2024

Efficacy of stellate ganglion block in treatment of electrical storm: a systematic review and meta-analysis.

Pouya Motazedian, Nicholas Quinn, George A Wells, Nickolas Beauregard, Eric Lam, Marie-Eve Mathieu, William Knoll, Graeme Prosperi-Porta, Valentina Ly, Simon Parlow and 8 more

Registry-linked trialAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07722052 (Diaphragmatic Ultrasound and Spirometry After Ultrasound-guided Stellate Ganglion Block), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07722052 completednot on this map

Diaphragmatic Ultrasound and Spirometry After Ultrasound-guided Stellate Ganglion Block: a Prospective Observational Study

Typeobservational_patient_registrySponsorJose Manuel López GonzálezRan2024 to 2026Enrolled15ConditionsStellate Ganglion Block, Diaphragm Ultrasound, Hemidiaphragmatic ParalysisArmsUltrasound-guided stellate ganglion block
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Pouya Motazedian *CAPITAL Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Nicholas Quinn *Department of Medicine, University of Ottawa, Ottawa, ON, Canada.
George A WellsDivision of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Nickolas BeauregardSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
Eric LamThe Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Marie-Eve MathieuDepartment of Medicine, University of Ottawa, Ottawa, ON, Canada.
William KnollDepartment of Medicine, University of Ottawa, Ottawa, ON, Canada.
Graeme Prosperi-PortaCAPITAL Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Valentina LyDepartment of Medicine, University of Ottawa, Ottawa, ON, Canada.
Simon ParlowCAPITAL Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Pietro Di SantoCAPITAL Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Omar Abdel-RazekCAPITAL Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Richard JungCAPITAL Research Group, Division of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Trevor SimardDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester Minnesota, MN, USA.
Jacob C JentzerDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester Minnesota, MN, USA.
Rebecca MathewDivision of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
F Daniel RamirezDivision of Cardiology, University of Ottawa Heart Institute, Ottawa, ON, Canada.
Benjamin HibbertDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester Minnesota, MN, USA. Hibbert.Benjamin@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrical storm (ES) is a life-threatening condition of recurrent ventricular arrhythmias (VA) in a short period of time. Percutaneous stellate ganglion blockade (SGB) is frequently used - however the efficacy is undefined. The objective of our systematic review was to determine the efficacy of SGB in reducing VA events and mortality among patients with ES. A search of Medline, EMBASE, Scopus, CINAHL and CENTRAL was performed on February 29, 2024 to include studies with adult patients (≥ 18 years) with ES treated with SGB. Our outcomes of interest were VA burden pre- and post-SGB, and in-hospital/30-day mortality. A total of 553 ES episodes in 542 patients from 15 observational studies were included. Treated VAs pre- and post-SGB were pooled from eight studies including 383 patients and demonstrated a decrease from 3.5 (IQR 2.25-7.25) to 0 (IQR 0-0) events (p = 0.008). Complete resolution after SGB occurred in 190 of 294 patients (64.6%). Despite this, in-hospital or 30-day mortality remained high occurring in 140 of 527 patients (random effects prevalence 22%). Repeat SGB for recurrent VAs was performed in 132 of 490 patients (random effects prevalence 21%). In conclusion, observational data suggests SGB may be effective in reducing VAs in ES. Definitive studies for SGB in VA management are needed. Study protocol: PROSPERO - registration number CRD42023430031.

Indexed as

Autonomic Nerve BlockStellate GanglionHumansTachycardia, VentricularTreatment OutcomeVentricular FibrillationElectrical stormMeta-analysisStellate ganglion blockSystematic ReviewVentricular arrhythmiaVentricular Electrical Storm

Identifiers

PMID39433834
PMCPMC11494072

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.