Evidence map›Paper›PMID 39432179›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Factors affecting the syncopal episodes in pediatric vasovagal syncope.

Shuo Wang, Yali Peng, Ping Liu, Jing Liu, Zhixiang He, Duping Peng, Hong Cai, Yuwen Wang, Runmei Zou, Cheng Wang

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In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shuo WangDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Yali PengSection of Science and Education, The First People's Hospital of Changde City, Changde, Hunan, 415000, China.
Ping LiuDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Jing LiuThe Children's Cardiothoracic Vascular Center, Chenzhou First People's Hospital, Chenzhou, Hunan, 423000, China.
Zhixiang HeDepartment of Pediatrics, Hunan Children's Hospital, Changsha, Hunan, 410007, China.
Duping PengDepartment of Pediatrics, Changsha County Maternal and Child Health Care Hospital, Changsha, Hunan, 410100, China.
Hong CaiDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Yuwen WangDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Runmei ZouDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China.
Cheng WangDepartment of Pediatric Cardiovasology, Children's Medical Center, The Second Xiangya Hospital, Central South University, No.139 Renmin Middle Road, Changsha, Hunan, 410011, China. wangcheng2nd@csu.edu.cn.ORCID http://orcid.org/0000-0002-7120-0654

Funding

Department of Science and Technology of Hunan Province 2023SK4018Natural Science Foundation of Hunan Province 2023JJ30812Peking University First Hospital 2022CR59
6 · The paper itself

Abstract

objectiveTo investigate factors that influence the syncopal episodes in pediatric vasovagal syncope (VVS).

methodsA retrospective analysis was performed on the clinical data of 2908 children who were diagnosed with VVS for the first time between January 2001 and February 2023. The study examined the linear relationships among age, sex, height, weight, heart rate (HR), blood pressure, hemodynamic type, and head-up tilt test (HUTT) mode in relation to the onset of syncope.

results(1) Comparative analysis of intergroup differences revealed statistically significant variations in sex, age, height, weight, HR, systolic blood pressure, hemodynamic classification, and HUTT mode among syncopal episodes groups (P < 0.05); (2) Univariate analysis identified age, female, height, weight, VVS-cardioinhibited type (VVS-CI), VVS-mixed type (VVS-M) as potential risk factors for syncope episodes. Conversely, HR and sublingual nitroglycerin HUTT (SNHUT) emerged as potential protective factors against syncope episodes. (3) Multivariate analysis indicated that the frequency of syncope episodes increased by 0.27/0.02 for each unit increase in age/weight. When females compared to males and VVS-CI and VVS-M compared to VVS-vasoinhibited type (VVS-VI), the frequency of syncope episodes increased by 1.36, 0.53, and 0.66 respectively. Furthermore, SNHUT was associated with a reduction in the number of syncope episodes by 0.34 relative to basic HUTT.

conclusionFemale, age, weight, VVS-CI, and VVS-M were identified as independent risk factors for syncopal episodes, while SNHUT was recognized as an independent protective factor against syncopal episodes.

Indexed as

Syncope, VasovagalAdolescentAge FactorsBlood PressureBody WeightChildChild, PreschoolFemaleHeart RateHumansMaleRetrospective StudiesRisk FactorsSex FactorsTilt-Table TestChildrenProtective factorRisk factorsSyncopal episodesVasovagal syncope

Identifiers

PMID39432179

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.