Evidence map›Paper›PMID 39432067›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

Total flavonoids from Rosa rugosa Thunb.: A comprehensive review of its extraction and purification process, chemical composition, biological effect and applications.

Guangfeng Dong, Lina Lv, Gang Ding, Fengying Li, Pan Zhao, Jiangting Liu, Hongyan Liu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Guangfeng DongCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Lina LvShandong University of Traditional Chinese Medicine Second Affiliated Hospital, Jinan, 250001, China.
Gang DingPingyin Rosa Characteristic Industrial Center, Jinan, 250400, China.
Fengying LiPingyin Rosa Characteristic Industrial Center, Jinan, 250400, China.
Pan ZhaoCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China. 60030080@sdutcm.edu.cn.
Jiangting LiuCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China. 13105414185@163.com.
Hongyan LiuCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China. lhyan0@163.com.

Funding

A research project on the development plan for industries with Pingyin County characteristics KYC2022017Demonstration Research Project on In-depth Development and Clinical Transformation of Chinese Medicinal Materials and Formulas from Taoist Land with Food and Medicine in Shandong Province 2021CXGC010510
6 · The paper itself

Abstract

Rosa rugosa Thunb. is a kind of traditional Chinese medicine with homology of medicine and food in China for a long history. The total flavonoids from R. rugosa Thunb. (TFR), possessing antioxidant, anti-tumor, antidepressant, and antibacterial activities, can effectively prevent and treat cardiovascular, hyperglycemia, hyperlipidemia, and other diseases. However, few studies have focused on TFR analyses and no comprehensive review has yet been published. In order to provide a theoretical foundation and research direction for further study and development, this paper methodically reviewed the extraction and purification procedure, chemical composition, biological activity, toxicology, and application in food of TFR on the basis of previous research. A total of 102 distinct flavonoids have been isolated from R. rugosa Thunb. Further pharmacological activities and chemical analyses research will contribute to the development of TFR products in R. rugosa Thunb.

Indexed as

Drugs, Chinese HerbalFlavonoidsPlant ExtractsRosaAnimalsHumansDrugs, Chinese HerbalFlavonoidsPlant ExtractsChemical constituentsExtraction and purificationFlavonoidsPharmacologyRosa rugosa Thunb

Identifiers

PMID39432067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.