Evidence map›Paper›PMID 39432042›Full record

ReviewAdvances in neurobiology2024

The Emerging Landscape of the Cerebellum after a Pediatric Traumatic Brain Injury: From Diaschisis to Sociality.

Michael Donovan, Morgan Frentz, Anakaren Romero Lozano, Shripriya Rao, Madeline Rodriguez, Linda J Noble-Haeusslein

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael DonovanDepartment of Neurology, Dell Medical School, The University of Texas at Austin, Austin, TX, USA.
Morgan FrentzDepartment of Neurology, Dell Medical School, The University of Texas at Austin, Austin, TX, USA.
Anakaren Romero LozanoDepartment of Biomedical Engineering, Cockrell School of Engineering, The University of Texas at Austin, Austin, TX, USA.
Shripriya RaoDepartment of Neurology, Dell Medical School, The University of Texas at Austin, Austin, TX, USA.
Madeline RodriguezTexas Tech University Health Sciences Center, Lubbock, TX, USA.
Linda J Noble-HaeussleinDepartments of Neurology and Psychology, Dell Medical School and the College of Liberal Arts, The University of Texas at Austin, Austin, TX, USA. linda.noble@austin.utexas.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is an expanding interest in the cerebellum in the context of focal and diffuse traumatic injuries to the cerebral cortex. In the adult brain, preclinical studies have revealed acute as well as progressive loss of Purkinje cells in the cerebellum coincident with microglial activation. This pathogenesis, remote to the site of the primary injury, is termed "diaschisis." Here we consider traumatic injuries to the developing brain, where the cerebellum likewise undergoes neurodegeneration. As injury is superimposed on a young brain, long-term adverse consequences may reflect diaschisis that is compounded by disruption of brain development.

Indexed as

Brain Injuries, TraumaticCerebellumChildHumansMicrogliaPurkinje CellsCerebellumDiaschisisPediatric traumatic brain injuriesSociality

Identifiers

PMID39432042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.